Results 81 to 90 of about 1,617,233 (339)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
COMPETITION ASPECTS IN THE AI ACT – NAVIGATING THE MURKY WATERS OF THE ABUSIVE PRACTICES IN A DECENTRALISED VIRTUAL WORLD [PDF]
Challenges of the Knowledge SocietyThe whole European construction, based on the three initial European Communities (namely, the European Coal and Steel Community, the European Economic Community and the European Atomic Energy Community) were built with several goals in mind, one of ...
Iulian BĂICULESCU
doaj
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Статистика и экономика, 2016 The study volume, structure and dynamics of investment companies Moscow region will be carried out using the methods ofeconomic-statistical, financial and economic analysis, includingmethods of statistical observation methods grouping detail anddata ...
Svetlana N. Zhuravleva
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
PSL Quarterly Review, 2002 Very few economic terms are used as much as competitiveness in economics. This article deals with the different meanings of competitiveness, at the level of a firm, at the level of the local area, and at the level of the country. It analyzes the problems of consistency among the available definitions and among the indicators used to measure ...
CELLINI, Roberto, SOCI A.
openaire +5 more sources
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Scientific ReportsThis study examined the psychometric properties of the Chinese version of the Multidimensional Competitive Orientation Inventory (Ch-MCOI) in adults from Mainland China.
Yuqian Wang +4 more
doaj +1 more source
Future InternetDigital forensics systems are complex applications consisting of numerous individual components that demand substantial computing resources. By adopting the concept of microservices, forensics applications can be divided into smaller, independently ...
Fragkiskos Ninos +3 more
doaj +1 more source