Results 91 to 100 of about 231,421 (295)
Grand challenges for the spatial information community
The spatial information (SI) community has an opportunity to address major societal and scientific problems including public health, climate change, air pollution, transportation, and others. Beyond the significant contributions made by the SI community,
Leye Wang, Ouri Wolfson
doaj +1 more source
Educational asymmetries in the making: Science Fair Competitions as Proxies of the Economic Development [PDF]
Croatia does not score well in the human development index, rate of employment, or development of the high tech sector - to mention only a few indicators that hinder good prospects for improvement. Also, Croatian high school students are at the bottom of European rankings on performance in science and mathematics and their interest in career in science
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Synthetic biology is an interdisciplinary field that brings together engineering and biology concepts alongside the arts and social sciences to develop solutions to pressing problems in our world.
Iain George+9 more
doaj +1 more source
Synthetic biology and biosecurity: challenging the ‘myths’
Synthetic biology, a field that aims to ‘make biology easier to engineer’, is routinely described as leading to an increase in the ‘dual use’ threat, i.e.
Catherine eJefferson+2 more
doaj +1 more source
Tangled Nature: a model of evolutionary ecology [PDF]
We discuss a simple model of co-evolution. In order to emphasise the effect of interaction between individuals the entire population is subjected to the same physical environment. Species are emergent structures and extinction, origination and diversity are entirely a consequence of co-evolutionary interaction between individuals.
arxiv
Dynamical Analysis of a Lotka-Volterra Competition Model with both Allee and Fear Effect [PDF]
Population ecology theory is replete with density dependent processes. However trait-mediated or behavioral indirect interactions can both reinforce or oppose density-dependent effects. This paper presents the first two species competitive ODE and PDE systems where an Allee effect, which is a density dependent process and the fear effect, which is non ...
arxiv
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Darwinian Adverse Selection [PDF]
We develop a model to study the role of rationality in economics and biology. The model's agents differ continuously in their ability to make rational choices. The agents' objective is to ensure their individual survival over time or, equivalently, to maximize profits.
arxiv
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source