Results 81 to 90 of about 2,499,667 (343)
Predicting coexistence of plants subject to a tolerance-competition trade-off
, 2013 Ecological trade-offs between species are often invoked to explain species coexistence in ecological communities. However, few mathematical models have been proposed for which coexistence conditions can be characterized explicitly in terms of a trade-off.
Etienne, Rampal S. +2 more
core +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Fisher vs. the Worms: Extraordinary Sex Ratios in Nematodes and the Mechanisms that Produce Them
Cells, 2021 Parker, Baker, and Smith provided the first robust theory explaining why anisogamy evolves in parallel in multicellular organisms. Anisogamy sets the stage for the emergence of separate sexes, and for another phenomenon with which Parker is associated ...
Justin Van Goor +2 more
doaj +1 more source
, 2011 Laws of nature take center stage in philosophy of science. Laws are usually believed to stand in a tight conceptual relation to many important key concepts such as causation, explanation, confirmation, determinism, counterfactuals etc.
Hüttemann, Andreas +2 more
core +1 more source
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
How self-regulation, the storage effect and their interaction contribute to coexistence in stochastic and seasonal environments [PDF]
, 2019 Explaining coexistence in species-rich communities of primary producers remains a challenge for ecologists because of their likely competition for shared resources.
Barraquand, Frederic, Picoche, Coralie
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Life, 2019 Reporter genes have contributed to advancements in molecular biology. Binding of an upstream regulatory protein to a downstream reporter promoter allows quantification of the activity of the upstream protein produced from the corresponding gene.
Takefumi Moriya +7 more
doaj +1 more source
Local cellular neighborhood controls proliferation in cell competition
Molecular Biology of the Cell, 2017 Cell competition is a quality-control mechanism through which tissues eliminate unfit cells. Automated microscopy with deep-learning image analysis was used to measure single-cell behavior during competition.
Anna Bove +5 more
semanticscholar +1 more source
An Overview of Agent-Based Models in Plant Biology and Ecology.
Annals of Botany, 2020 Agent-based modeling (ABM) has become an established methodology in many areas of biology, ranging from the cellular to the ecological population and community levels. In plant science, two different scales have predominated in their use of ABM.
Bo Zhang, D. DeAngelis
semanticscholar +1 more source