Results 121 to 130 of about 285,043 (352)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Functional Methods for Studying Sperm–Zona Pellucida Interaction in Mammals

Methods and Protocols
The initial molecular events mediating mammalian sperm binding to the zona pellucida (ZP) of the oocyte are highly complex and still not fully elucidated.
Natalie Zelenkova, Veronika Kraus, Alexandra Maresova, Zuzana Pilsova, Aneta Pilsova, Barbora Klusackova, Eva Chmelikova, Katerina Komrskova, Pavla Postlerova   +8 more
doaj   +1 more source

Laboratory measurements and modeling of metal-humic interactions under estuarine conditions. [PDF]

, 2002
Equilibrium dialysis was used to measure Co- and Cu-binding by an isolated peat humic acid (PHA) in controlled laboratory experiments under simulated estuarine conditions: ionic strengths of 0.005-0.7 M in NaCl and mixed Na-Mg-Ca chloride solutions, with
Hamilton-Taylor, J., Postill, A. S., Tipping, E., Harper, M. P.   +3 more
core  

Competitive binding assays of the Cry8 toxin and toxin-DNA complex using the BBMVs from the target larvae.

, 2013
A. Competitive binding of the Cry8Ea1 toxin and Cry8Ea1 toxin-DNA complex with the BBMVs of H. parallela larvae. B. Competitive binding of the Cry8Ca2 toxin and Cry8Ca2 toxin-DNA complex with the BBMVs of A. corpulenta larvae.
Bingjie Ai (492597), Shuyuan Guo (307629), Feng Li (30515), Dongmei Feng (492598), Jie Li (15030)   +4 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Ligand-binding properties of XaffOBP9, a Minus-C odorant-binding protein from Xyleborus affinis (Coleoptera: Curculionidae: Scolytinae)

Frontiers in Physiology
Xyleborus affinis, one of the most important pests of rubber trees, has caused severe damage to the natural rubber industry in Hainan province. The ability to detect host plants through a sensitive and specific olfactory system is crucial for Xyleborus ...
Qian Wang, Xiang Zhou, Kai Zhang, Lei Qin, Qi Wu, Linan Deng, Zheyuan Xu, Jixing Guo   +7 more
doaj   +1 more source

Long non-coding RNA DLEU2 drives EMT and glycolysis in endometrial cancer through HK2 by competitively binding with miR-455 and by modulating the EZH2/miR-181a pathway [PDF]

, 2021
Peixin Dong, Ying Xiong, Yosuke Konno, Kei Ihira, Noriko Kobayashi, Junming Yue, Hidemichi Watari   +6 more
openalex   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Design, synthesis, and evaluation of a novel fluorescent probe for competitive fluorescence polarization assay to screen galectin-8 inhibitors

Acta Pharmaceutica
In the present work, we describe the design, synthesis, and evaluation of a galectin-8-binding fluorescent probe designed for a competitive fluorescence polarization (FP) assay for screening new galectin-8N inhibitors. The probe was characterized for its
Purić Edvin, Marinović Marina, Kojek Zala, Kahl-Knutson Barbro, Leffler Hakon, Nilsson Ulf J., Anderluh Marko, Mravljak Janez   +7 more
doaj   +1 more source

Additional file 4 of Knockdown of LINC00665 inhibits proliferation and invasion of breast cancer via competitive binding of miR-3619-5p and inhibition of catenin beta 1

, 2020
Minhao Lv, Qixin Mao, Juntao Li, Jianghua Qiao, Xiuchun Chen, Suxia Luo   +5 more
openalex   +1 more source