Results 131 to 140 of about 1,539,544 (287)

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Development and application of a competitive ELISA for the detection of antibodies against <i>Salmonella</i> Abortusequi in equids. [PDF]

J Clin Microbiol, 2023
Guo K, Guo W, Liu D, Zhang W, Yang Y, Zhang Z, Li S, Wang J, Chu X, Wang Y, Hu Z, Wang X.   +11 more
europepmc   +1 more source

ELISA and competitive ELISA assays demonstrated WSSV VP31 binding to the PmLamr was specific.

, 2016
(A) ELISA analysis of MBP-VP31 binding to the PmLamr-His in a dose-dependent manner. PmLamr-His (2 μg/ well) was coated to a 96-well plate and incubated with various amounts of purified MBP-VP31. MBP was added as negative control.
Guang-Hsiung Kou (248714), Wang-Jing Liu (248698), Yi-Chieh Li (562161), Chu-Fang Lo (203152)   +3 more
core   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

Advanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park, Yeongkag Kwon, Yeonjin Lim, Jeong Woo Park, Hyun Jung Ji, Dongwook Lee, Jueun Lee, Sung‐Ho Yun, Sungho Jeong, Ho Seong Seo, Kun Cho, Cheol‐Heui Yun, Ok‐Jin Park, Seung Hyun Han   +13 more
wiley   +1 more source

Preparation of Anti-Zearalenone IgY and Development of an Indirect Competitive ELISA Method for the Measurement of Zearalenone in Post-Fermented Tea. [PDF]

Foods, 2023
Qiu T, Zhang H, Lei H, Zhang L, Zhang Y, Shen X, Xu B, Zhu J, Xiao W, Zheng J, Chen J.   +10 more
europepmc   +1 more source

Development of a C. trachomatis-Specific Competitive Pgp3 ELISA

, 2013
Background Chlamydia trachomatis (CT) DNA testing of genital samples principally from symptomatic persons provides information about active infection only, and is unlikely to represent true prevalence of current and past infection in the population ...
McClure, M., Horner, P., Warrener, L., Samuel, D., Wills, G.   +4 more
core   +1 more source

A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy

Advanced Science, EarlyView.
A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao, Yufei Lan, Min‐Goo Lee, Jinjun He, Yueran Pan, Eunji Kim, Xin Fu, Sungwook Jung, Wanxia Lu, Jinyue Fan, Haoxiang Chen, Yuanbo Zhao, Yuling Xu, Jong Seung Kim, Chao Zhang   +14 more
wiley   +1 more source

Production and evaluation of anti-BP26 monoclonal antibodies for the serological detection of animal brucellosis

Frontiers in Veterinary Science
Brucella BP26 proves to be a highly immunogenic antigen with excellent specificity in brucellosis detection. In China, the authorized use of the Bp26-deleted vaccine M5ΔBP26 for preventing small ruminant brucellosis highlights the importance of ...
Xiaohan Guo, Mingjun Sun, Yu Guo, Yao Wu, Xin Yan, Mengda Liu, Jiaqi Li, Xiangxiang Sun, Xiaoxu Fan, Haobo Zhang, Shufang Sun, Jianlong Wang, Dehui Yin   +12 more
doaj   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

The study of direct ELISA and competitive ELISA for rabbit metallothionein: Correlation of induction with zinc

, 2000
On the basis of the purification of metallothionein (MT) from human fetal liver, the purified polyclonal antibody of rabbit anti-human MT-1 was prepared. Direct enzyme-linked immunosorbent assay (ELISA) for MT in rabbit tissues was established.
Ying, L.I.U., Yu Meimin, Hongwei, R.E.N., Meimin, Y.U., Ren Hongwei, Binggen, R.U., Liu Ying, Ru Binggen, Junheng, Zheng, Dang Weiwei, Weiwei, Dang, Zheng Junheng   +11 more
core   +1 more source