Results 111 to 120 of about 1,539,544 (287)

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Competitive ELISA for Serodiagnosis of Bluetongue: A Refinement [PDF]

Journal of Veterinary Diagnostic Investigation, 1993
A, Afshar, G C, Dulac, C, Dubuc, J E, Pearson, G A, Gustafson   +4 more
openaire   +2 more sources

Characterization of monoclonal and polyclonal antibodies to bovine enteric coronavirus: Establishment of an efficient ELISA for antigen detection in feces [PDF]

, 1989
Monoclonal antibodies to bovine enteric coronavirus (BEC) were produced. Additionally, polyclonal antibodies were made in rabbits and guinea pigs and extracted from the yolk of immunized hens.
Eichhorn, Werner, Czerny, C. P.
core   +1 more source

A.A. Blok, Colori e parole, traduzione e nota introduttiva di Alessandra Elisa Visinoni

, 2016
Traduzione a cura di Alessandra Elisa Visinoni del saggio di Aleksandr Blok, Sobranie sočinenij v šesti tomach, Leningrad, Chudožestvennaja literatura, 1982, vol. IV, pp.
Visinoni, Alessandra Elisa
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Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Elisa Lucinda: artigo 227 [Constituindo]

, 2016
Ensino Fundamental::Séries Iniciais::Pluralidade CulturalEnsino Fundamental Final::Pluralidade CulturalApresenta vídeo da série Constituindo. Neste episódio a atriz Elisa Lucinda lê o artigo 227 da Constituição Federal do Brasil de 1988.
TV Câmara
core   +2 more sources

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Design of ELISA-based diagnostic system for detection of enterohaemorrhagic Escherichia coli

Iranian Journal of Microbiology
Background and Objectives: Escherichia coli (E. coli) O157:H7 is an intestinal pathogen of humans and animals, which causes serious gastrointestinal, urinary tract infection and hemolytic uremic syndrome.
Mohammad Javad Rezaei, Maryam Eidi, Seyed Ali Mirhosseini, Rouhollah Kazemi, Mohammad Javad Motamedi, Soghra Khani, Jafar Amani   +6 more
doaj   +1 more source

Softbundlaamalla kasvua : case: Elisa Oyj [PDF]

, 2019
Tässä opinnäytetyössä tutkittiin softbundlaamista apuvälineenä kalliimpien, premium-liittymien myynnissä Elisalla. Tutkimuksen tarkoituksena oli selvittää, millä tavoin softbundlaamista voidaan hyödyntää Elisan eri tuotteiden ja palveluiden myynnissä.
Räihä, Atte
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