Results 101 to 110 of about 1,539,544 (287)

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

Establishment and Preliminary Application of Highly Sensitive Competitive ELISA for Folic Acid

Shipin gongye ke-ji
In order to achieve high sensitivity and rapid detection of folic acid, this study established a highly sensitive competitive enzyme-linked immunosorbent assay (cELISA) by preparing folic acid monoclonal antibody and optimizing the detection system.
Yao WANG, Yanfei LI, Jinbo CAO, Xiyan YANG, Jiaxiang HUANG, Mingyue HUANG, Lu HAN, Kaile WANG, Xiujin CHEN, Zhaozhou LI, Min ZHANG, Huaibin KANG   +11 more
doaj   +1 more source

Nanobody-horseradish peroxidase fusion protein as an ultrasensitive probe to detect antibodies against Newcastle disease virus in the immunoassay

Journal of Nanobiotechnology, 2019
Background Sensitive and specific antibodies can be used as essential probes to develop competitive enzyme-linked immunosorbent assay (cELISA).
Yamin Sheng, Kun Wang, Qizhong Lu, Pinpin Ji, Baoyuan Liu, Jiahong Zhu, Qingyuan Liu, Yani Sun, Jingfei Zhang, En-Min Zhou, Qin Zhao   +10 more
doaj   +1 more source

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

Advanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun, Shuwei Dang, Dazhi Zhou, Lixian Ding, Xun Sun, Wei Suo, Jirui Niu, Qingzhu Yang, Zhicheng Zhang, Yanyan Sun, Jinxing Li, Zhongsheng Chen, Tao Ban, Yingji Wang, Tianzhu Li, Ming Liu, Guodong Li   +16 more
wiley   +1 more source

Two nanobody-based immunoassays to differentiate antibodies against genotype 1 and 2 porcine reproductive and respiratory syndrome virus

Animal Diseases
Porcine reproductive and respiratory syndrome virus (PRRSV) infection causes significant economic loss to the global pig industry. Genotype 1 and 2 PRRSV (PRRSV-1 and -2) infections have been reported in China, Europe and America. For accurate prevention,
Xu Chen, Yueting Chang, Lu Zhang, Xinyu Zhao, Zhihan Li, Zhijie Zhang, Pinpin Ji, Qingyuan Liu, Jiakai Zhao, Jiahong Zhu, Baoyuan Liu, Xinjie Wang, Yani Sun, Qin Zhao   +13 more
doaj   +1 more source

Detection and Quantitation of Gluten in Fermented-Hydrolyzed Foods by Antibody-Based Methods: Challenges, Progress, and a Potential Path Forward

Frontiers in Nutrition, 2019
Celiac disease (CD) affects ~1 in 141 individuals in the United States, requiring adherence to a strict gluten-free diet. The Codex Standard and the European Commission states that gluten level of gluten-free foods must not exceed 20 ppm.
Rakhi Panda, Eric A. E. Garber
doaj   +1 more source

A szöveti transzglutamináz ellenes IgG antitest kimutatása ELISA módszerrel

, 2017
A coeliakia vezető szerepet tölt be az ételintoleranciák között, a malabszorpciós szindróma kialakulásának leggyakoribb oka. A jellemző kóros immunválaszt a gabonafélék fehérjéje a glutén váltja ki.
Molnár, Mercédesz
core  

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Elisa Lucinda: artigo 227 [Constituindo]

, 2011
Ensino Fundamental Final::Pluralidade CulturalEnsino Fundamental::Séries Iniciais::Pluralidade CulturalApresenta vídeo da série Constituindo. Neste episódio a atriz Elisa Lucinda lê o artigo 227 da Constituição Federal do Brasil de 1988.
TV Câmara
core   +2 more sources