Results 181 to 190 of about 1,539,544 (287)

Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis

open access: yesAdvanced Science, EarlyView.
Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang   +9 more
wiley   +1 more source

Integrated Laboratory Evaluation of Rift Valley Fever Virus Antibodies Using the Competitive ELISA and Virus Neutralization Test. [PDF]

open access: yesPathogens
Dafalla OM   +10 more
europepmc   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

open access: yesAdvanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao   +6 more
wiley   +1 more source

Quantification of amygdalin in various seeds using indirect competitive ELISA

open access: yes, 2007
아미그달린(amygdalin)은 시안배당체(cyanogenic glycoside comp -ound) 물질로 보통 과일의 씨앗이나 견과류 그리고 몇몇 식물에 존재한다. Emulsin에 의해 benzaldehyde, cyanide, 그리고 두 분자의 포도당으로 분해되는데, 여기서 cyanide는 신경독성 물질로 메스꺼움, 구토, 두통, cyanosis의 원인이 되며 심하면 죽음에 이르게 되므로 위험하다.
이수정
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang   +9 more
wiley   +1 more source

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