Results 51 to 60 of about 1,539,544 (287)

Establishment of an indirect competitive ELISA for sulfadimethoxine

Shipin yu jixie
ObjectiveTo establish an indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) for the detection of sulfadimethoxine (SDM) in animal-derived foods.MethodsAn artificial antigen is synthesized by conjugating SDM with carrier proteins by the ...
Han Lu, Huang Mingyue, Yu Xiang, Li Sijia, Cao Jinbo, Wang Yao, Kang Huaibin   +6 more
doaj   +1 more source

Bluetongue Virus Infections in Cattle Herds of Manabí Province of Ecuador

Pathogens, 2021
Bluetongue (BT) is a viral disease transmitted by Culicoides (Diptera: Ceratopogonidae) to domestic and wild ruminants. Infections in cattle are mainly subclinical, but severe necrotic and hemorrhagic illness and death may occur depending on the strain ...
Euclides De la Torre, Nixon Moreira, Claude Saegerman, Kris De Clercq, María Salinas, Alex Maldonado, David Jarrín, María Sol Vaca, Silvia Pachacama, Jorge Espinoza, Hipatia Delgado, Maritza Barrera   +11 more
doaj   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Development and validation of a competitive ELISA based on virus-like particles of serotype Senecavirus A to detect serum antibodies

AMB Express, 2021
Virus-like particles (VLPs) are high-priority antigens with highly ordered repetitive structures, which are similar to natural viral particles. We have developed a competitive enzyme-linked immunosorbent assay (cELISA) for detecting antibodies directed ...
Manyuan Bai, Rui Wang, Shiqi Sun, Yun Zhang, Hu Dong, Huichen Guo   +5 more
doaj   +1 more source

Clinical Utility of a Commercial LAM-ELISA Assay for TB Diagnosis in HIV-Infected Patients Using Urine and Sputum Samples [PDF]

, 2010
Background: The accurate diagnosis of TB in HIV-infected patients, particularly with advanced immunosuppression, is difficult. Recent studies indicate that a lipoarabinomannan (LAM) assay (Clearview-TB (R)-ELISA) may have some utility for the diagnosis ...
Peter, J, Peter Jonathan, Richard van Zyl Smit, Zumla, A, Green, Clare, Sechi Leonardo, Sechi, L, Badri Motasim, Hoelscher Michael, Dawson, R, Badri, M, Green, C, Blackburn, J, Whitelaw, Andrew, Laurence Brunet, Pai, Madhukar, Meldau, Richard, Sechi, Leonardo Antonio, Badri, Motasim, Andrew Whitelaw, Brunet Laurence, Zumla Alimuddin, Smit, Richard van Zyl, Whitelaw Andrew, Dawson Rodney, Dawson, Rodney, Dheda, Keertan, Clare Green, Brunet, Laurence, Davids, Virginia, Blackburn Jonathan, Zyl-Smit, Richard N. van, Lenders, Laura, Ling, D, Sharma, S, Roberts, Teri, Leonardo Sechi, Surendra Sharma, Madhukar Pai, Pai Madhukar, Meldau, R, Virginia Davids, Dheda, K, Sharma, Surendra, Daphne Ling, Jonathan Blackburn, Sharma Surendra, van Zyl Smit, Richard, Keertan Dheda, Davids Virginia, Rodney Dawson, Green Clare, Hoelscher, Michael, Lenders, L, Sechi, Leonardo, Teri Roberts, Michael Hoelscher, Richard Meldau, Roberts Teri, Lenders Laura, van Zyl Smit Richard, Peter, Jonathan, Davids, V, Whitelaw, A, Meldau Richard, Hoelscher, M, Ling, Daphne, Pai, M, Jonathan Peter, Motasim Badri, Blackburn, Jonathan, Zumla, Alimuddin, Dheda Keertan, Smit, RV, Roberts, T, Laura Lenders, Ling Daphne, Alimuddin Zumla, Brunet, L   +78 more
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Detection of Bluetongue Group-Specific Antibody by Competitive ELISA [PDF]

Journal of Veterinary Diagnostic Investigation, 1990
a2 that react with the major core protein VP7 5,7 to the reference Mab 3-17-A3 b in the cELISA. 3 Three hybridomas, 7D3A.2, 8A3B.6, and 8B1B.1, a2 were prepared against BTV17, and their Mab’s were found to be reactive with BT serotypes 1-20. The Mab’s bound to VP7 (designated VP9) 2 and did not react with epizootic hemorrhagic disease (EHD) virus.
C, House, J A, House, M L, Berninger
openaire   +2 more sources

Serological surveillance of bluetongue virus in cattle in central Iran [PDF]

Veterinaria Italiana, 2013
The aim of this study was to evaluate the seroprevalence and distribution of antibodies to the bluetongue virus (BTV) among dairy Holstein cattle of central Iran.
Vahid Noaman, Edris Shirvani, Seyed Mohammad Hosseini, Amir Hossein Shahmoradi, Mohammad Reza Heidari, Hamid Raiszadeh, Morteza Kamalzadeh, Masoume Bahreyari   +7 more
doaj   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source