Results 101 to 110 of about 145,979 (303)

Aggregation without Loss of Optimality in Competitive Location Models [PDF]

open access: yes, 2006
In the context of competitive facility location problems demand points often have to be aggregated due to computational intractability. However, usually this spatial aggregation biases the value of the objective function and the optimality of the ...
Frank Plastria, Lieselot Vanhaverbeke
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Competitive balance in complex professional sports leagues [PDF]

open access: yes, 2008
Competitive balance is seen as crucial to the viability of professional sports leagues, and it has been a central concern of sports economists, industry practitioners and fans. But the concept is complex and ill-defined. The theoretical approach in this
Kringstad, Morten
core  

Decentralized Market Processes to Stable Job Matchings with Competitive Salaries [PDF]

open access: yes
We analyze a decentralized trading process in a basic labor market where heterogeneous firms and workers meet directly and randomly, and negotiate salaries with each other over time.
Satoru Fujishige, Bo Chen, Zaifu Yang
core   +2 more sources

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Tell Me Where You Are and I’ll Tell You What You Want: Using Location Data to Improve Marketing Decisions

open access: yesGfK Marketing Intelligence Review, 2016
Location data has become more and more accessible. Smartphone applications such as location-based services collect location data on a large scale.
Spann Martin   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

An explicitly dynamic competitive facilities location model

open access: yes, 2002
Previous studies in competitive facilities location have almost always considered a single period problem with static treatment of market conditions. Location problems are strategic in nature.
Gobaco, Bryan O.
core  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

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