Results 41 to 50 of about 1,151,001 (290)

Optimizing Cost Function in Imperialist Competitive Algorithm for Path Coverage Problem in Software Testing [PDF]

Journal of Artificial Intelligence and Data Mining, 2018
Search-based optimization methods have been used for software engineering activities such as software testing. In the field of software testing, search-based test data generation refers to application of meta-heuristic optimization methods to generate ...
M. A. Saadtjoo, S. M. Babamir
doaj   +1 more source

Modeling Firm Search and Innovation Trajectory Using Swarm Intelligence

Algorithms, 2023
We developed a swarm intelligence-based model to study firm search across innovation topics. Firm search modeling has primarily been “firm-centric,” emphasizing the firm’s own prior performance.
Ren-Raw Chen, Cameron D. Miller, Puay Khoon Toh   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Competition and Defaults in Online Search

SSRN Electronic Journal, 2023
This paper offers the first systematic quantitative assessment of default-option interventions designed to mitigate Google's search dominance. By analyzing interventions in the European Economic Area (EEA), Russia, and Turkey, we find that across all three cases, changes to default settings effectively reduced Google's market share.
Decarolis, Francesco, Li, Muxin, Paternollo, Filippo   +2 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Crisscross Optimization Algorithm and Monte Carlo Simulation for Solving Optimal Distributed Generation Allocation Problem

Energies, 2015
Distributed generation (DG) systems are integral parts in future distribution networks. In this paper, a novel approach integrating crisscross optimization algorithm and Monte Carlo simulation (CSO-MCS) is implemented to solve the optimal DG allocation ...
Xiangang Peng, Lixiang Lin, Weiqin Zheng, Yi Liu   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Large-scale multiobjective competitive swarm optimizer algorithm based on regional multidirectional search

Complex & Intelligent Systems
Competitive swarm optimizer (CSO) based on multidirectional search plays a crucial role in addressing large-scale multiobjective optimization problems (LSMOPs).
Xuenan Zhang, Debao Chen, Fangzhen Ge, Feng Zou, Lin Cui   +4 more
doaj   +1 more source

A Hybrid Heuristic Harmony Search Algorithm for the Vehicle Routing Problem With Time Windows

IEEE Access
In this paper, we present a hybrid heuristic method based on the harmonic search algorithm to solve the vehicle routing problem with time windows. The importance of efficient path planning in logistics and supply chain management is emphasized herein ...
Yang Zhang, Jiacheng Li
doaj   +1 more source

Price-Directed Search, Product Differentiation and Competition

Review of Industrial Organization, 2023
AbstractEspecially in many online markets, consumers can readily observe prices, but may need to inspect products further to assess their suitability. We study the effects of product differentiation and search costs on competition and market outcomes in a tractable model of price-directed consumer search.
Obradovits, Martin, Plaickner, Philipp
openaire   +3 more sources