Results 51 to 60 of about 1,151,001 (290)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Journal of Cloud Computing: Advances, Systems and ApplicationsIn competitive sports and other role-based team activities, selecting a squad with strong mutual compatibility is critical for coordinated execution and overall performance.
Yanfeng Li +4 more
doaj +1 more source
Efficient Competition through Cheap Talk: Competing Auctions and Competitive Search without Ex Ante Price Commitment [PDF]
, 2013 We consider a frictional two-sided matching market in which one side uses public cheap-talk announcements so as to attract the other side. We show that if the first-price auction is adopted as the trading protocol, then cheap talk can be perfectly ...
Che, Yeon-Koo, Kircher, Philipp
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The relationship between competitive advantage and customer satisfaction in Islamic Banks in Yemen
مجلة الدراسات الاجتماعية, 2015 This study aimed to identify the relationship between the competitive advantage and customer satisfaction in Islamic banks in Yemen. The researcher used the descriptive analytical method to answer the research questions and examine the hypotheses.
مراد محمد النشمي +1 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
‘Subjective’ price search and price competition [PDF]
International Journal of Industrial Organization, 1986 Abstract In this paper we study price rivalry between two firms facing a population of imperfectly informed buyers. The two sellers are geographically dispersed and consumers search for the lowest price. The competitive process either suffers from cyclical instability or stabilises at that price at which no buyer searches.
P. Garella, J. J. Gabszewicz
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Parallel Optimization Algorithm for Competitive Facility Location
Mathematical Modelling and Analysis, 2015 A stochastic search optimization algorithm is developed and applied to solve a bi-objective competitive facility location problem for firm expansion.
Algirdas Lančinskas +2 more
doaj +1 more source
Large neighborhood search for the most strings with few bad columns problem [PDF]
, 2016 In this work, we consider the following NP-hard combinatorial optimization problem from computational biology. Given a set of input strings of equal length, the goal is to identify a maximum cardinality subset of strings that differ maximally in a pre ...
Blesa Aguilera, Maria Josep +3 more
core +3 more sources