Results 31 to 40 of about 1,114,682 (316)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Concept, Measurement, and Ideology of "National Competitiveness" [PDF]
, 2011 The author of this paper reviewing the perceptions of competitiveness reveals the origin and ambiguity of the concept of “national competitiveness” which is mostly confused with that of development of countries and competitiveness of their enterprises ...
Szentes, Tamás
core
The Scientific Competitiveness of Nations [PDF]
, 2014 We use citation data of scientific articles produced by individual nations in different scientific domains to determine the structure and efficiency of national research systems.
Cimini, Giulio +2 more
core +3 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Unlocking the Code to Continuous Innovation: A Study of Key Determinants for Serial Innovators
Administrative SciencesThis study investigates the fundamental role of collaboration in promoting a culture of continuous innovation in companies, driving them to become serial innovators, as evidenced by their industrial property registrations. Furthermore, it explores, in an
Cátia Rosário +2 more
doaj +1 more source
Demographic change and regional competitiveness: The effects of immigration and ageing [PDF]
, 2007 The demographic profile of a region is usually seen as a slowly changing background phenomenon in the analysis of regional competitiveness and regional growth. However, regional demographic change can have a significant impact on regional competitiveness
Poot, Jacques
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Automated irrigation of apple trees based on dendrometer sensors
Agricultural Water ManagementThis study evaluates the efficiency of an automated irrigation system using dendrometer sensors in apple orchards and compares it to a standard grower commercial irrigation approach based on soil moisture sensors.
Thainná Waldburger +6 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source