Results 41 to 50 of about 413,598 (267)

Valuing Services in Trade : A Toolkit for Competitiveness Diagnostics

, 2014
The Service Trade Competitiveness Diagnostic (STDC) Toolkit is part of a larger agenda of trade competitiveness work developed by the World Bank’s International Trade Unit in recent years.
Zavacka, Veronika, Taglioni, Daria, van der Marel, Erik, Hollweg, Claire H., Sáez, Sebastián   +4 more
core   +1 more source

The transition process and institutions: on the issue of the standard of living in the countries of Central and Eastern Europe — members of the European Union

Baltic Region, 2021
The aim of this article is to adjust the technique of comparing the standard of living in 11 countries of Central and Eastern Europe that became members of the European Union (EU) during 2004-2013 (EU-11) and 15 countries of Western, Northern and ...
Igor V. Pilipenko
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Unlocking the Code to Continuous Innovation: A Study of Key Determinants for Serial Innovators

Administrative Sciences
This study investigates the fundamental role of collaboration in promoting a culture of continuous innovation in companies, driving them to become serial innovators, as evidenced by their industrial property registrations. Furthermore, it explores, in an
Cátia Rosário, Celeste Varum, Anabela Botelho   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Automated irrigation of apple trees based on dendrometer sensors

Agricultural Water Management
This study evaluates the efficiency of an automated irrigation system using dendrometer sensors in apple orchards and compares it to a standard grower commercial irrigation approach based on soil moisture sensors.
Thainná Waldburger, Thomas Anken, Marianne Cockburn, Achim Walter, Matthias Hatt, Camilo Chiang, Hassan-Roland Nasser   +6 more
doaj   +1 more source

Institutional contributions to agricultural producer price stability

Agricultural and Food Economics, 2022
This paper compares the main intersectoral and national agricultural institutions in Russia and Switzerland during the period 2004–2019 and uses data from the Food and Agriculture Organization (FAO), an ordinary least squares model and fixed-effects ...
Daria Loginova, Stefan Mann
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source