Results 51 to 60 of about 2,267,242 (386)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
The Economics of Small States; Observations from Scotland - a Comment
Welsh Economic Review, 2016 The historical perspective provided by John Kay in his article presents a compelling rationale for re-thinking what a state is and what it should do. The production relationships and consumption patterns that characterise today’s interconnected global ...
James R. Wilson
doaj +1 more source
SSRN Electronic Journal, 2005 The effects of (private, small‐scale) piracy on the pricing behavior of producers of information goods are studied within a unified model of vertical differentiation. Although information goods are assumed to be perfectly differentiated, demands are interdependent because the copying technology exhibits increasing returns to scale. We characterize the
Picard, Pierre +2 more
openaire +8 more sources
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The comparative economic analysis of Hungarian and German apple production of good standard
International Journal of Horticultural Science, 2009 The profitability of the Hungarian apple production considering firms producing on high standard is not lagged behind significantly from that of German firms, moreover in certain cases it reflects a more positive situation.
F. Apáti
doaj +1 more source
Smooth transition regression model relating inflation to economic growth in Tunisia
Journal of Economic Structures, 2023 Since its independence, Tunisia has embarked on monetary and financial sector reforms aimed at boosting economic growth. However, these reforms have not been effective due to inflation pressures in this country.
Hamdi Becha, Maha Kalai, Kamel Helali
doaj +1 more source
The Inner Functioning of Local Governance Networks in Centralized Countries: A ‘Brave New World’?
Social Sciences, 2023 Local governance networks are increasingly seen as the big idea to cope with issues that are complex enough in scope and scale to require a diversity of expertise and resources. While conventional narrative has posited that local networks are optimal for
Patrícia Silva +4 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Unlocking the Code to Continuous Innovation: A Study of Key Determinants for Serial Innovators
Administrative SciencesThis study investigates the fundamental role of collaboration in promoting a culture of continuous innovation in companies, driving them to become serial innovators, as evidenced by their industrial property registrations. Furthermore, it explores, in an
Cátia Rosário +2 more
doaj +1 more source
Effects of atmospheric discharges on wind farms performance: a review study
Renewable Energy and Environmental Sustainability, 2022 One of the factors that influence the energy projects’ performance is the atmospheric conditions. Atmospheric discharges are a recurrent and natural phenomenon, that for the energy sector, represent a risk for the system functioning due to the ...
Mello Gisela +2 more
doaj +1 more source