Results 171 to 180 of about 844,522 (297)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Complement C4d Informs the Differential Diagnosis of Inflammatory Demyelinating CNS Diseases. [PDF]

Neurol Neuroimmunol Neuroinflamm
Landt C, Held F, Kolotourou K, Guranda M, Vakrakou AG, Franz J, Thomas C, Schmiedeknecht MUH, Bergann K, Wrzos C, Endmayr V, Tsaktanis T, Zechel S, Ancău M, Misgeld T, Hakroush S, Hametner S, Rothhammer V, Höftberger R, Hemmer B, Stadelmann C, Nessler S.   +21 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Complement activation in anti-glomerular basement membrane disease before and after treatment with imlifidase. [PDF]

Clin Kidney J
Tyrberg L, Uhlin F, Alam S, Sonesson E, Hellmark T, Blom AM, Segelmark M.   +6 more
europepmc   +1 more source

Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL)

, 2019
Stephanie Savelli, Robert Roubey, Kathryn J. Kitzmiller, Danlei Zhou, Haikady N. Nagaraja, Evan Mulvihill, Fatima Barbar‐Smiley, Stacy P. Ardoin, Yee Ling Wu, C. Yung Yu   +9 more
openalex   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Mutations in UMOD Contribute to the Pathogenesis of ADTKD-UMOD by Influencing the Function of Complement Factor H. [PDF]

J Cell Mol Med
Xie Q, Bai L, Gong K, Hu N, Chen Y.
europepmc   +1 more source

Branched Spherical CR structures on the complement of the figure eight knot [PDF]

, 2013
Elisha Falbel, Jieyan Wang
openalex   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Complement-mediated and direct activation of human neutrophils induced by <i>Premolis semirufa</i> caterpillar toxins. [PDF]

Front Immunol
Gabrili JJM, Megale ÂAA, Pidde G, Woodruff TM, Tambourgi DV.   +4 more
europepmc   +1 more source