Results 201 to 210 of about 3,085,481 (399)

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Transcriptomic atlas reveals organ-specific disease tolerance in sickle cell mice

open access: yesBlood Advances
: Sickle cell disease (SCD) is the most common genetic disease in the world and a societal challenge. SCD is characterized by multiorgan injury related to intravascular hemolysis.
Anne Grunenwald   +9 more
doaj  

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

open access: yesNeuron, 2012
D. Schafer   +9 more
semanticscholar   +1 more source

Shì as a complementizer

open access: yesJournal of Chinese Linguistics
ABSTRACT: In this article, it is argued that a purely functional and semantically bleached shì in Mandarin could in many contexts be best analyzed as a complementizer. As such, it is comparable to English that and functions as an (optional) introducer of the clausal arguments.
openaire   +2 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Complementizer Drop And IP Complementation in Japanese

open access: yesKansas Working Papers in Linguistics, 2000
The main purpose of the present paper is to provide a principled account for a phenomenon called "Complementizer Drop" in the dialects of Japanese and its related phenomena in teens of the head-raising approach without recourse to the ECP or GB-type approach, under the assumption that the complement clause without a complementizer is not CP but a ...
openaire   +3 more sources

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

open access: yesFEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

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