Results 271 to 280 of about 2,630,357 (343)

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh, Yoon Hee Shin, Soo Hyun Ahn, Su Yee Mon, Soo Jean Shin, Woo‐Jin Lee, Yoonhyuk Jang, Myoung‐Jin Jang, Soon‐Tae Lee   +8 more
wiley   +1 more source

Role of Complement Component 9 in Bone Health: Causal Evidence in Humans and Mechanistic Studies in Mice. [PDF]

Calcif Tissue Int
Ohlsson C, Törnqvist AE, Nilsson KH, Nethander M, Wu J, Li L, Koskela A, Movérare-Skrtic S.   +7 more
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Identification of novel blood-borne soluble binding partners of factor H-related proteins. [PDF]

Sci Rep
Tang J, Woerz F, Beyer T, Boldt K, Rathi S, Zhao S, Wolfram L, Ueffing M, Clark SJ.   +8 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Yersinia enterocolitica O:3 Outer Membrane Vesicles as a Platform for Complement Activation. [PDF]

J Extracell Vesicles
Battaglino C, Bodnaruk I, Czyszczoń P, Skurnik M, Filip-Psurska B, Jarych D, Maciejewska A, Gadzinowski M, Malik K, Potocka I, Migdał P, Kruszakin R, Cedzyński M, Kasperkiewicz K, Lukasiewicz J, Świerzko AS.   +15 more
europepmc   +1 more source

Immune podocyte injury in autoimmune glomerular diseases. [PDF]

Front Immunol
Zhu H, Sun J, Yan Y, Liu P, Huang Y.
europepmc   +1 more source

Complement C9 deficiency as a novel risk factor for invasive Candida esophagitis in children: a single case in-depth analysis. [PDF]

BMC Pediatr
Zheng G, Zhang J, Peng K, Tang L, Tan Z, Gu W, Wang Y.   +6 more
europepmc   +1 more source

"Non-Specific" Complement-fixing Activity of Cloudy Avian Sera: Part I. Preliminary Observations.

, 1949
Christine E. Rice
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