Results 21 to 30 of about 3,430 (122)

Inhibitors of Complement Activity in Human Breast‐Milk: A Proposed Hypothesis of Their Physiological Significance

open access: yesMediators of Inflammation, Volume 8, Issue 2, Page 69-75, 1999., 1999
Several natural components abundant in the fluid phase of human breast‐milk have been shown to be inhibitors of complement activation in vitro, particularly the classical pathway. These include lysozyme, lactoferrin, lactalbumin alpha and other ligand chelators, complement regulator proteins and other specific soluble inhibitors of complement ...
Michael Oladipo Ogundele
wiley   +1 more source

Inactivation of the particulate methane monooxygenase (pMMO) in Methylococcus capsulatus (Bath) by acetylene [PDF]

open access: yes, 2015
Acetylene (HCCH) has a long history as a mechanism-based enzyme inhibitor and is considered an active-site probe of the particulate methane monooxygenase (pMMO).
Chan, Sunney I.   +11 more
core   +1 more source

Studies on Human Complement: The Relationship of C3, C5, ß1c and ß1a

open access: yesJournal of Immunology, 1971
Nine proteins of the complement system have been isolated from isolectric focusing columns. The pI values were: C1, 4.99; C4, 6.40; C2, 5.52; C3, 5.75; C5, 4.10; C6, 6.00; C7, 5.59; C8, 5.60 and 6.50; and C9, 4.72. Recovery was between 50% and 100% for
R. A. Nelson
semanticscholar   +1 more source

A Computational and Experimental Study of the Regulatory Mechanisms of the Complement System [PDF]

open access: yes, 2010
The complement system is key to innate immunity and its activation is necessary for the clearance of bacteria and apoptotic cells. However, insufficient or excessive complement activation will lead to immune-related diseases. It is so far unknown how the
A Krarup   +67 more
core   +4 more sources

Polyhalogenated Carbohydrates: Synthesis and Applications of Sugar Halides from Fluorine to Iodine

open access: yesEuropean Journal of Organic Chemistry, Volume 27, Issue 16, April 22, 2024.
The societal importance of sucralose (a trichlorinated disaccharide) doesn't fade over time. This review focuses on the synthesis and applications of polyhalogenated carbohydrates incorporating fluorine, chlorine, bromine, and iodine atoms. An overview of the current state of the art of sugar inter‐halides is also presented.
Olivier Lessard   +2 more
wiley   +1 more source

Biomolecular Corona of Gold Nanoparticles: The Urgent Need for Strong Roots to Grow Strong Branches

open access: yesSmall, Volume 20, Issue 15, April 11, 2024.
This review presents a critical analysis of the current methodologies to decipher bio‐nano interactions by analyzing the biomolecular corona using gold nanoparticles as a case study. The study aims for a collective effort of the nano‐community through standardization of methodologies (for synthesis, characterization, and omics), data sharing, and ...
Luca Boselli   +4 more
wiley   +1 more source

THE DERIVATION OF TWO DISTINCT ANAPHYLATOXIN ACTIVITIES FROM THE THIRD AND FIFTH COMPONENTS OF HUMAN COMPLEMENT [PDF]

open access: yes, 1968
Anaphylatoxin activity was derived from both human C'5 and C'3 molecules. This was achieved in the case of C'5 by interaction with trypsin or with EAC'4, oxy2a, 3.
Cochrane, C. G., Müller-Eberhard, H. J.
core   +3 more sources

Orofacial Granulomatosis among Pediatric Patients Well Controlled by Corticosteroid Treatment: A Rare Case Series

open access: yesCase Reports in Pediatrics, Volume 2024, Issue 1, 2024.
Orofacial granulomatosis (OFG) is a rare disease entity characterized by nonnecrotizing granulomatous inflammation in the oral and maxillofacial regions, typically characterized by recurrent or persistent edema, primarily in the lips and occasionally in the gingiva. OFG is often associated with Crohn’s disease and sarcoidosis, and an accurate diagnosis
Taku Kimura   +7 more
wiley   +1 more source

Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis

open access: yesTranslational Psychiatry, 2020
Potentially neurotoxic systems involved in traumatic and degenerative diseases of the brain were assessed in acute psychosis. Astrocyte-derived exosomes (ADEs) and neuron-derived exosomes (NDEs) were immunoprecipitated from plasma of ten untreated first ...
E. Goetzl   +5 more
semanticscholar   +1 more source

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