C1 Complex: An Adaptable Proteolytic Module for Complement and Non-Complement Functions
Complement C1 is the defining component of the classical pathway. Within the C1qC1r2C1s2 complex, C1q functions as a molecular scaffold for C1r2C1s2 and C1q binding to its ligands activates these two serine proteases.
Jinhua Lu, U. Kishore
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JOURNAL/nrgr/04.03/01300535-202503000-00027/figure1/v/2024-06-17T092413Z/r/image-tiff Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus, leading to long-term cognitive impairment.
Jing Wang +11 more
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A Case of Duodenal Edema-related Undiagnosed Hereditary Angioedema. [PDF]
Kawara F +3 more
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Immunologic abnormalities in myelofibrosis with activation of the complement system.
B. Gordon, M. Coleman, P. Kohen, N. Day
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Presentation of an extraordinary colic: abdominal pain as the first and only utterance of an acquired C1-inhibitor deficiency. [PDF]
Hanevelt J +1 more
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Conformational dynamics of complement protease C1r inhibitor proteins from Lyme disease- and relapsing fever-causing spirochetes. [PDF]
Roy S +5 more
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Recombinant human C1 esterase inhibitor as prophylactic treatment in idiopathic non-histaminergic angioedema. [PDF]
Alizadeh Aghdam M +7 more
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Pseudomonas aeruginosa and the Complement System: A Review of the Evasion Strategies. [PDF]
González-Alsina A +3 more
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Complement activation and complement control proteins in acute pancreatitis.
J. Whicher +6 more
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