Quantitation of 55 Common Human Plasma Proteins in Healthy Young Adults and Correlation with Body Mass Index and Dietary Patterns [PDF]
, 2010 Plasma biomarkers are a useful tool for monitoring dietary exposures and the development of chronic disease. Measuring multiple biomarkers at once provides a more complete characterization of phenotype than measuring single markers.
Ahmed El-Sohemy +8 more
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Quantification of human C1 esterase inhibitor protein using an automated turbidimetric immunoassay [PDF]
, 2019 BACKGROUND: Impaired levels or function of C1 inhibitor (C1-INH) results in angioedema due to increased bradykinin. It is important to distinguish between angioedema related to C1-INH deficiency and that caused by other mechanisms, as treatment options ...
El-Shanawany, Tariq +12 more
core +2 more sources
The pathophysiology of the complement system in leprosy [PDF]
, 1991 The complement system, which consists of a group of proteins and glycoproteins, generally serves to amplify the effects of the interaction of antigen with antibody.
Ramanathan, V D
core
Complement system and alcoholic liver disease [PDF]
, 2008 Alcoholic liver disease (ALD) is a well recognized and growing health problem worldwide. ALD advances from fatty liver to inflammation, necrosis, fibrosis and cirrhosis.
Bykov, Igor
core
Old Drugs To Treat Resistant Bugs: Methicillin-Resistant Staphylococcus aureus Isolates with mecC Are Susceptible to a Combination of Penicillin and Clavulanic Acid. [PDF]
, 2015 β-Lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA) is mediated by the expression of an alternative penicillin-binding protein 2a (PBP2a) (encoded by mecA) with a low affinity for β-lactam antibiotics.
Ba, Xiaoliang +9 more
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Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) [PDF]
, 2008 The prostate is a site of high expression of serine proteinases including members of the kallikrein-related peptidase (KLK) family, as well as other secreted and membrane-anchored serine proteinases.
Adams, Mark N. +6 more
core +1 more source
The X-ray structure of carboxypeptidase a inhibited by a thiirane mechanism-based ihibitor [PDF]
, 2010 The three-dimensional X-ray crystal structure of carboxypeptidase A, a zinc-dependent hydrolase, covalently modified by a mechanism-based thiirane inactivator, 2-benzyl-3,4-epithiobutanoic acid, has been solved to 1.38 Å resolution.
Avilés, Francesc X. +4 more
core +1 more source
Staphylococcus aureus virulence factors and disease [PDF]
, 2013 Staphylococcus aureus is a major cause of nosocomial infections worldwide, especially methicillin-resistant S. aureus. Patients subjected to broad-spectrum antibiotics and immunosuppressive therapies have higher risk of infection by this microorganism.
Batistão, Deivid W. F. +5 more
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The Role of Exopolyphosphatase in Neisseria meningitidis Infection
, 2009 The development of vaccines against serogroup B Neisseria meningitidis to reduce the morbidity and mortality of meningococcal disease is a major public health priority.
Zhang, Qian, Zhang, Qian
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Humoral Immunological Factors and Nitric Oxide Levels in HIV Patients with Low CD4+ T-Lymphocytes Count [PDF]
, 2012 Purpose: This study determined the plasma levels of nitric oxide (effector molecule in intracellular killing by phagocytes), regulators (C3 inactivator and C1 inhibitor) and factors (C4 and C3c) of Complement system and immunoglobulin classes (IgG, IgA ...
Arinola, GO, Olaniyi, JA
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