Results 131 to 140 of about 49,543 (282)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Evolved DNAzymes and Stable Activation Chemistry Enable High‐Efficiency DNA Ligation

Chemistry – A European Journal, EarlyView.
In vitro selection of pre‐structured DNA libraries and chemical screening of alternative activation groups yielded trans‐acting DNAzymes with faster ligation rates and enhanced DNA substrate stability. The combination of C3S1 DNAzymes and phosphobenzimidazole‐activated DNA substrates provides improved DNA ligation performance, offering promise for ...
Connor Nurmi, Gemma Mendonsa, Mengdi Bao, Yingfu Li   +3 more
wiley   +1 more source

Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications

Chemistry – A European Journal, EarlyView.
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley   +1 more source

Expanding the Diagnostic Lens: Mast Cell Activation Syndromes and the Hidden Spectrum of Angioedema Associated Mortality in COVID-19. [PDF]

Acad Forensic Pathol
Sison EL, Aban JL.
europepmc   +2 more sources

Protective Effects of Auricularia auricula Polysaccharides on Acute Lung Injury by Regulating Intestinal Flora and Metabolism

Food Frontiers, EarlyView.
Auricularia auricula polysaccharides (AAP; 100, 200, and 400 mg/kg) protect against acute lung injury (ALI) by dose‐dependently remodeling the gut microbiota and modulating associated metabolic pathways via the gut‐lung axis, thereby enhancing pulmonary anti‐inflammatory and antioxidant capacity to ultimately prevent tissue damage.
Haili Niu, Fangjia Zhao, Qi Wang, Min Li, Yuan Li, Ivan Kurtovic, Zitong Zhang, Yahong Yuan, Tianli Yue   +8 more
wiley   +1 more source

BrkA Protein ofBordetella pertussisInhibits the Classical Pathway of Complement after C1 Deposition

, 2001
Michael Barnes, Alison A. Weiss
openalex   +1 more source

Clinical Experience with Berotralstat in Patients with Hereditary Angioedema with Normal C1-Esterase Inhibitor: A Commented Case Series

Journal of Asthma and Allergy
Henry J Kanarek,* Drew Austin Saville Mutschelknaus* Kanarek Allergy, Asthma & Immunology, Leawood, KS, USA*These authors contributed equally to this workCorrespondence: Henry J Kanarek, Tel +1 (913) 451-8555, Fax +1 (913) 327-8553, Email ...
Kanarek HJ, Mutschelknaus DAS
doaj  

Human Astrovirus Coat Protein Inhibits Serum Complement Activation via C1, the First Component of the Classical Pathway

, 2007
Rheba S. Bonaparte, Pamela S. Hair, Deepa Banthia, Dawn Marshall, Kenji M. Cunnion, Neel K. Krishna   +5 more
openalex   +2 more sources

Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos, Alba Regueira‐Iglesias, Berta Suárez‐Rodríguez, Alba Sánchez‐Barco, Iryna Kuz, Marta Relvas, Susana Belén Bravo, Carlos Balsa‐Castro, Inmaculada Tomás   +8 more
wiley   +1 more source

Effect of Nanoparticles Type and Content on the Antimicrobial Activity of Magnetoelectric Polymer‐Based Composites

Macromolecular Bioscience, EarlyView.
Magnetoelectric P(VDF‐TrFE) nanocomposites containing CFO or Fe3O4 nanoparticles were developed to generate electroactive microenvironments under magnetic stimulation. At 1 Hz, particularly with 20% CFO, strong antimicrobial effects were observed against E. coli and S. aureus. This approach highlights the potential of magnetically activated surfaces to
Joana Moreira, Margarida M. Fernandes, Vitor Correia, Daniela M. Correia, Carmen R Tubio, Vesna Lazic, Senentxu Lanceros‐Mendez   +6 more
wiley   +1 more source