Results 121 to 130 of about 21,229 (271)

Blood protein-polymer adsorption: Implications for understanding complement-mediated hemoincompatibility

, 2011
The aim of this study was to create polymeric materials with known properties to study the preconditions for complement activation. Initially, 22 polymers were screened for complement activating capacity. Based on these results, six polymers (P1-P6) were
Jenny P. Rosengren-Holmberg, Nilsson Ekdahl, Kristina,, Lambris, JD,, Bo Nilsson, Nilsson, Bo,, Nicholls, Ian A.,, Hui Chen, John D. Lambris, Anna E. Engberg, Chen, H,, Engberg, Anna E.,, Lambris, John D.,, Chen, Hui,, Kristina N. Ekdahl, Ian A. Nicholls, Rosengren-Holmberg, Jenny P.,   +15 more
core   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

The complement factsbook /

, 2000
The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins.
Morley, Bernard J., Walport, Mark.
core  

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

Drug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz, Linus Korsmeier, Andreas Thomas, Mario Thevis   +3 more
wiley   +1 more source

Fish Scales: A Multifunctional Biomaterial from Nature

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

Bioinformatic analysis of single nucleotide variants in the F12 gene associated with hereditary angioedema

Медицинская иммунология
Hereditary angioedema (HAE) is a genetically determined disorder, a primary immunodeficiency involving complement system dysfunction. In most patients, the disease is characterized by a deficiency of C1 inhibitor (type I HAE) or impaired functional ...
A. V. Sedykh, Yu. V. Ostankova, A. N. Schemelev, Areg A. Totolian   +3 more
doaj   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

Anti-ischemia/reperfusion of C1 inhibitor in myocardial cell injury via regulation of local myocardial C3 activity

, 2006
C3 is common to all pathways of complement activation augmenting ischemia/reperfusion (I/R)-induced myocardial injury and cardiac dysfunction. Complement inhibition with the complement regulatory protein, C1 inhibitor (C1INH), obviously exerts ...
Bin Zeng, Gan, Xiang, Qin, Gangjian, Liu, Dongxu, Chunhua Li, Chu, Honggang, Gong Liang, Yanxia Wu, Guosheng Lin, Fu, Jinrong, Lin, Guosheng, Wu, Yanxia, Liang, Gong, Yu, Xiaolan, Honggang Chu, Jinan Li, Wu, Zhiwei, Gangjian Qin, Xiaolan Yu, Dongxu Liu, Li, Chunhua, Jinrong Fu, Xiang Gan, Li, Jinan, Zhiwei Wu, Zeng, Bin   +25 more
core   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Effect of Wall Material Concentrations on Microencapsulation Efficiency and Oxidative Stability of Pomegranate Seed Oil

Food Safety and Health, EarlyView.
This study demonstrates how different wall materials influence the efficiency, stability, and quality of oil encapsulation, highlighting optimal formulations that enhance protection against oxidation. ABSTRACT The purpose of this study is to evaluate how different compositions of wall materials affect the efficiency and oxidative stability of ...
Hala Rabea Damen, Nameer Khairullah Mohammed, Anis Shobirin Meor Hussin, Belal J. Muhialdin, Muammar Talib Hamad, Arpit Shrivastava   +5 more
wiley   +1 more source