Results 131 to 140 of about 48,228 (282)

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

open access: yesChemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar   +13 more
wiley   +1 more source

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

open access: yesDrug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz   +3 more
wiley   +1 more source

Bioinformatic analysis of single nucleotide variants in the F12 gene associated with hereditary angioedema

open access: yesМедицинская иммунология
Hereditary angioedema (HAE) is a genetically determined disorder, a primary immunodeficiency involving complement system dysfunction. In most patients, the disease is characterized by a deficiency of C1 inhibitor (type I HAE) or impaired functional ...
A. V. Sedykh   +3 more
doaj   +1 more source

Fish Scales: A Multifunctional Biomaterial from Nature

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

The tangled web [PDF]

open access: yes, 1990
Dorsch, Walter   +2 more
core   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

open access: yesFood Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee   +4 more
wiley   +1 more source

Effect of Wall Material Concentrations on Microencapsulation Efficiency and Oxidative Stability of Pomegranate Seed Oil

open access: yesFood Safety and Health, EarlyView.
This study demonstrates how different wall materials influence the efficiency, stability, and quality of oil encapsulation, highlighting optimal formulations that enhance protection against oxidation. ABSTRACT The purpose of this study is to evaluate how different compositions of wall materials affect the efficiency and oxidative stability of ...
Hala Rabea Damen   +5 more
wiley   +1 more source

Marine Macroalgae as a Safe Healthy Food While Meeting Food Security Challenges Arising From Climate Changes

open access: yesFood Safety and Health, EarlyView.
Planned harvesting and processing of marine macroalgae could meet future global food needs and mitigate fuel‐originated carbon dioxide responsible for climate change. Microalgal foods are nutritious and safe. The utilization of macroalgae would avoid environmental problems arising from the release of overgrowing macroalgae caused by heatwaves, which ...
Upali Samarajeewa
wiley   +1 more source

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

open access: yesiMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang   +13 more
wiley   +1 more source

Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos   +8 more
wiley   +1 more source

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