Results 151 to 160 of about 40,238 (270)

Humán dendritikus sejtek működésének szabályozása komplementfehérjék és receptoraik által; exosomák jelentősége a T-sejt válasz kialakításában = Regulation of the function of dendritic cells by complement proteins and receptors; the role of exosomes in the development of T-cell response [PDF]

, 2011
A dendritikus sejtek (DC-k) érését számos stimulus indukálja, mint például a gyulladásos körülmények vagy mikrobiális termékek jelenléte. A szervezetbe kerülő antigén a komplementrendszer aktiválódása következtében opszonizált formában van jelen, ami az
Bajtay, Zsuzsa, Erdei, Anna, Isaák, Andrea   +2 more
core  

Gut‐derived bacterial vesicles carrying lipopolysaccharide promote microglia‐mediated synaptic pruning

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION Growing evidence links gut microbiota (GM) to Alzheimer's disease (AD). Elevated lipopolysaccharide (LPS) levels, a Gram‐negative bacteria component, are found in AD brains, but how LPS breaches the blood–brain barrier (BBB) remains unclear.
Xiaoduo Zhao, Jiayi Yu, Bin Xu, Zhi Xu, Xia Lei, Shilong Han, Shangfei Luo, Can Zhang, Guoping Peng, Jing Li, Jie Yu, Yi Ling, Zhongqin Fan, Wei Mo, Ying Yang, Jing Zhang   +15 more
wiley   +1 more source

Proangiogenic properties of complement protein C1q can contribute to endometriosis

Frontiers in Immunology
Endometriosis (EM) is defined as the engraftment and proliferation of functional endometrial-like tissue outside the uterine cavity, leading to a chronic inflammatory condition.
Chiara Agostinis, Miriam Toffoli, Gabriella Zito, Andrea Balduit, Silvia Pegoraro, Mariagiulia Spazzapan, Lorella Pascolo, Federico Romano, Giovanni Di Lorenzo, Alessandro Mangogna, Aurora Santin, Beatrice Spedicati, Beatrice Spedicati, Erica Valencic, Giorgia Girotto, Giorgia Girotto, Giuseppe Ricci, Giuseppe Ricci, Uday Kishore, Uday Kishore, Roberta Bulla   +20 more
doaj   +1 more source

Complement C1q essential for aeroallergen sensitization via CSF1R⁺ conventional dendritic cells type 2. [PDF]

J Allergy Clin Immunol, 2023
Moon HG, Eccles JD, Kim SJ, Kim KH, Kim YM, Rehman J, Lee H, Kanabar P, Christman JW, Ackerman SJ, Ascoli C, Kang H, Choi HS, Kim M, You S, Park GY.   +15 more
europepmc   +1 more source

Inhibition of the activation of Hageman factor (factor XII) by complement subcomponent C1q. [PDF]

, 1987
Esther H. Rehmus, Bruce M. Greene, B Everson, Oscar D. Ratnoff   +3 more
openalex   +1 more source

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

Annals of Neurology, Volume 98, Issue 2, Page 317-328, August 2025.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr., Bruce A. C. Cree, Stephen L. Hauser   +2 more
wiley   +1 more source

Neutrophil heterogeneity in complement C1q expression associated with sepsis mortality. [PDF]

Front Immunol, 2022
Trzeciak A, Mongre RK, Kim MR, Lim K, Madero RA, Parkhurst CN, Pietropaoli AP, Kim M.   +7 more
europepmc   +1 more source

Ofatumumab for the Treatment of Anti‐Neurofascin 155 Autoimmune Nodopathy: A Case Series

Brain and Behavior, Volume 15, Issue 8, August 2025.
Summarize the key messages of this paper Ofatumumab treatment led to significant clinical, imaging, and electrophysiological improvements in four patients with anti‐NF155 AN.1. No adverse reactions to ofatumumab were observed in any of the patients. Ofatumumab has great potential for treating anti‐NF155 AN.3. ABSTRACT Introduction Autoimmune nodopathy (
Kalam Choi, Peicai Fu, Jinyi Yan, Zhijun Li   +3 more
wiley   +1 more source

Safety and Target Engagement of Complement C1q Inhibitor ANX007 in Neurodegenerative Eye Disease: Results from Phase I Studies in Glaucoma. [PDF]

Ophthalmol Sci, 2023
Sun Y, Wirta D, Murahashi W, Mathur V, Sankaranarayanan S, Taylor LK, Yednock T, Fong DS, Goldberg JL.   +8 more
europepmc   +1 more source

Human serum amyloid P component oligomers bind and activate the classical complement pathway via residues 14-26 and 76-92 of the A chain collagen-like region of C1q. [PDF]

, 1993
S C Ying, Anita Gewurz, Hao Jiang, H Gewurz   +3 more
openalex   +1 more source