Results 151 to 160 of about 41,476 (260)

Proangiogenic properties of complement protein C1q can contribute to endometriosis

Frontiers in Immunology
Endometriosis (EM) is defined as the engraftment and proliferation of functional endometrial-like tissue outside the uterine cavity, leading to a chronic inflammatory condition.
Chiara Agostinis, Miriam Toffoli, Gabriella Zito, Andrea Balduit, Silvia Pegoraro, Mariagiulia Spazzapan, Lorella Pascolo, Federico Romano, Giovanni Di Lorenzo, Alessandro Mangogna, Aurora Santin, Beatrice Spedicati, Beatrice Spedicati, Erica Valencic, Giorgia Girotto, Giorgia Girotto, Giuseppe Ricci, Giuseppe Ricci, Uday Kishore, Uday Kishore, Roberta Bulla   +20 more
doaj   +1 more source

Inhibition of the activation of Hageman factor (factor XII) by complement subcomponent C1q. [PDF]

, 1987
Esther H. Rehmus, Bruce M. Greene, B Everson, Oscar D. Ratnoff   +3 more
openalex   +1 more source

Dysregulation of Different Modes of Programmed Cell Death in Rheumatoid Arthritis Fibroblast‐Like Synoviocyte

International Journal of Rheumatic Diseases, Volume 28, Issue 10, October 2025.
ABSTRACT Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by chronic synovitis and skeletal joint deformities, often accompanied by systemic symptoms. Over the past few decades, various susceptibility factors for RA have been revealed, and numerous therapeutic drugs have been developed, including analgesics, glucocorticoids ...
Xiaorong Zhi, Hong Zhu, Xiaoyan Sun, Zhaoxia Wang, Lin Wang, Guanhua Song   +5 more
wiley   +1 more source

Complement C1q essential for aeroallergen sensitization via CSF1R⁺ conventional dendritic cells type 2. [PDF]

J Allergy Clin Immunol, 2023
Moon HG, Eccles JD, Kim SJ, Kim KH, Kim YM, Rehman J, Lee H, Kanabar P, Christman JW, Ackerman SJ, Ascoli C, Kang H, Choi HS, Kim M, You S, Park GY.   +15 more
europepmc   +1 more source

IgG4‐Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets

Allergy, Volume 80, Issue 10, Page 2738-2754, October 2025.
ABSTRACT IgG4, the least abundant IgG subclass in humans, is increasingly recognised for its involvement in allergic and autoimmune pathologies. Its unique properties, such as the tendency to form half‐molecules (one heavy chain and one light chain) and its generally non‐inflammatory nature, distinguish it from other IgG subclasses.
Louisa Tedesco, Syed B. Ali, Baran Erman, Safa Baris, Harshita Pant, Pravin Hissaria, Yelda Bilginer, Damon J. Tumes, Gökhan Cildir   +8 more
wiley   +1 more source

Neutrophil heterogeneity in complement C1q expression associated with sepsis mortality. [PDF]

Front Immunol, 2022
Trzeciak A, Mongre RK, Kim MR, Lim K, Madero RA, Parkhurst CN, Pietropaoli AP, Kim M.   +7 more
europepmc   +1 more source

Human serum amyloid P component oligomers bind and activate the classical complement pathway via residues 14-26 and 76-92 of the A chain collagen-like region of C1q. [PDF]

, 1993
S C Ying, Anita Gewurz, Hao Jiang, H Gewurz   +3 more
openalex   +1 more source

IgM Antibodies Targeting Malondialdehyde Promote Complement‐Mediated Liver Injury in Alcohol‐Related Liver Disease

Liver International, Volume 45, Issue 10, October 2025.
ABSTRACT Background and Aims Alcohol‐related liver disease (ALD) is associated with elevated blood immunoglobulin‐type M (IgM) levels and hepatic lipid peroxidation. Nevertheless, the functional relevance of systemic IgM targeting lipid peroxidation products during ALD is incompletely understood.
Dragana Rajcic, Beatriz Pereira da Silva, Taras Baranovskyi, Benedikt Simbrunner, Benedikt S. Hofer, Constanze Hoebinger, Tereza Duckova, Nikolina Papac‐Milicevic, Stephan Listabarth, Sabine Weber, Benjamin Vyssoki, Daniel König, Katharina Burger, Ina Bergheim, Christoph J. Binder, Mattias Mandorfer, Thomas Reiberger, Tim Hendrikx   +17 more
wiley   +1 more source

Safety and Target Engagement of Complement C1q Inhibitor ANX007 in Neurodegenerative Eye Disease: Results from Phase I Studies in Glaucoma. [PDF]

Ophthalmol Sci, 2023
Sun Y, Wirta D, Murahashi W, Mathur V, Sankaranarayanan S, Taylor LK, Yednock T, Fong DS, Goldberg JL.   +8 more
europepmc   +1 more source

Role of Complement Component C1q in the IgG-Independent Opsonophagocytosis of Group BStreptococcus [PDF]

, 1999
Peter Butko, A Nicholson-Weller, Michael R. Wessels   +2 more
openalex   +1 more source