Results 201 to 210 of about 994,718 (258)

Tree shrew model of early diabetic retinopathy reveals microvascular dysfunction and identifies phosphoserine aminotransferase 1 as a novel therapeutic target

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We developed an animal model of early diabetic retinopathy (DR) in the tree shrew by feeding a high‐fat and high‐sugar diet in combination with STZ. Physiological and biochemical index detection, hematoxylin and eosin staining, and transmission electron microscopy were performed to examine DR.
Min Qiu   +10 more
wiley   +1 more source

A Doxorubicin‐Loaded Liposomes Baghdadite System for Localized Osteosarcoma Therapy and Bone Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam   +8 more
wiley   +1 more source

Complement pathway dysregulation and astrocyte alterations in Down syndrome: evidence from postmortem brain tissue and iPSC-derived astrocytes. [PDF]

open access: yesActa Neuropathol Commun
Teles E Silva AL   +7 more
europepmc   +1 more source

Complement response to burn injury: systematic review and meta-analysis of patient and animal studies. [PDF]

open access: yesFront Immunol
Mulder PPG   +5 more
europepmc   +1 more source

Crystals as Rockets: Modulation of the Salient Temperature in Cocrystals by Solvent Mixture Composition

open access: yesAngewandte Chemie, EarlyView.
Compositionally engineered mixed solvated cocrystals enable modulation of thermosalient actuation. Guest ratio controls thermosalient temperature and propulsion intensity, providing a tunable platform for designing crystalline systems that exhibit stimuli‐responsive mechanical motion.
Ernesto A. Hernández‐Morales   +5 more
wiley   +1 more source

C2 complement deficiency in a 3-year old girl

open access: yesCentral European Journal of Immunology, 2008
Polańska, Bożena, Jankowski, Adam
openaire  

Sequential Homo‐ and Hetero‐Coupling of Isocyanide and Carbon Monoxide Mediated by Acyclic Imino(silyl)Silylene

open access: yesAngewandte Chemie, EarlyView.
We demonstrate the sequential reactions between an imino(hypersilyl)silylene and aryl isocyanide or carbon monoxide as a molecular‐level model of the Fischer–Tropsch process, providing systematic and detailed insight into C–C bond formation during the homologation of C1 building blocks.
Huaiyuan Zhu   +3 more
wiley   +1 more source

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