Results 191 to 200 of about 268,987 (334)

Decay-Accelerating Factor Suppresses Complement C3 Activation and Retards Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice [PDF]

, 2009
Viola Leung, Sheng Yun, Marina Botto, Justin C. Mason, Talat H. Malik, Wen‐Chao Song, Danielle Paixão-Cavalcante, Matthew C. Pickering, Joseph J. Boyle, Dorian O. Haskard   +9 more
openalex   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Proteolytic profiling of human plasma reveals an immunoactive complement C3 fragment. [PDF]

EMBO J
Demir F, Kovalenko E, Lassé M, Svenningsen EB, Bernth Jensen JM, Billing AM, Groeneveld K, Hutzfeldt A, Nilges L, Guerra JPL, Pietrzak-Lichwa KJ, Tan Y, Colby E, Hansen AG, Kurmasheva N, Olagnier D, Choi D, Richter MM, Laufer SD, Braun F, Johnson SA, Krüger M, Huber TB, Hoxha E, Steinmetz OM, Mrowka R, Melderis S, Saleem MA, Poulsen TB, Andersen GR, Thiel S, Troldborg A, Rinschen MM.   +32 more
europepmc   +1 more source

Dysregulation of adaptive immune responses in complement C3‐deficient patients [PDF]

, 2014
Pirkka T. Pekkarinen, Nelli Heikkilä, Kai Kisand, Pärt Peterson, Marina Botto, Mohamed R. Daha, Christian Drouet, Lourdes Isaac, Merja Helminen, Tari Haahtela, Seppo Meri, Hanna Jarva, T. Petteri Arstila   +12 more
openalex   +1 more source

Complement 3 (C3); C5a [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Free‐Volume Regulation Enables Significantly Enhanced Electrical Breakdown via Short‐Chain Molecular Spatial‐Positioning Intercalation into Poly(vinylidene fluoride)

Advanced Science, EarlyView.
An innovative molecular spatial‐positioning shimming strategy is developed to optimize the electrical properties of poly(vinylidene fluoride) (PVDF). By intercalating polyethylene wax (PE wax) short‐chain molecules into PVDF's free volume, the film achieves a significantly enhanced energy density of 32.67 J cm−3.
Ziyue Wang, Jiyang Xie, Wanbiao Hu
wiley   +1 more source

A cut above: atypical proteolysis endows complement C3 with non-canonical immune activities. [PDF]

EMBO J
West EE, Kemper C.
europepmc   +1 more source

A novel mutation in complement 2 accompanied by susceptibility variants in C3 glomerulonephritis: A case study

, 2019
Sha-sha Han, Xiao-juan Yu, Su-xia Wang, Fu-de Zhou, Feng Yu, Ming‐Hui Zhao   +5 more
openalex   +1 more source

Stability of C3 Convertase in the Rat Classical Complement Pathway [PDF]

, 1997
Akihiro Naito, Hidechika Okada
openalex   +1 more source