Results 81 to 90 of about 862,879 (325)

Development and Optimization of an ELISA to Quantitate C3(H2O) as a Marker of Human Disease

Frontiers in Immunology, 2019
Discovery of a C3(H2O) uptake pathway has led to renewed interest in this alternative pathway triggering form of C3 in human biospecimens. Previously, a quantifiable method to measure C3(H2O), not confounded by other complement activation products, was ...
Michelle Elvington, M. Kathryn Liszewski, Alexis R. Liszewski, Hrishikesh S. Kulkarni, Ramsey R. Hachem, Thalachallour Mohanakumar, Alfred H. J. Kim, John P. Atkinson   +7 more
doaj   +1 more source

Serum complement C3 levels are associated with nonalcoholic fatty liver disease independently of metabolic features in Chinese population

Scientific Reports, 2016
Serum complement C3 levels are closely associated with obesity and related metabolic disorders. This study aimed to investigate the association between serum complement C3 levels with non-alcoholic fatty liver disease (NAFLD). A cross-sectional study was
Chengfu Xu, Yi Chen, Lei Xu, M. Miao, Youming Li, Chaohui Yu   +5 more
semanticscholar   +1 more source

An Ultra‐Robust Memristor Based on Vertically Aligned Nanocomposite with Highly Defective Vertical Channels for Neuromorphic Computing

Advanced Functional Materials, EarlyView.
An ultra‐robust memristor based on SrTiO3‐CeO2 (S‐C) vertically aligned nanocomposite (VAN) achieving exceptional endurance of 1012 switching cycles via interface engineering. Artificial neural networks (ANNs) integrated with S‐C VAN memristors exhibit high training accuracy across multiple datasets.
Zedong Hu, Hongyi Dou, Jeremy B. Gan, Cun Li, Xuanyu Sheng, Juanjuan Lu, Abhijeet Choudhury, Jialong Huang, Yizhi Zhang, Zhongxia Shang, Ye Cao, Xinghang Zhang, Haiyan Wang   +12 more
wiley   +1 more source

Specific Evolution and Gene Family Expansion of Complement 3 and Regulatory Factor H in Fish

Frontiers in Immunology, 2020
The complement system comprises a large family of plasma proteins that play a central role in innate and adaptive immunity. To better understand the evolution of the complement system in vertebrates and the contribution of complement to fish immunity ...
Babak Najafpour, João C. R. Cardoso, Adelino V. M. Canário, Deborah M. Power   +3 more
doaj   +1 more source

Mechanochemistry‐Assisted Solvent‐Free Supramolecular Engineering for Atomic‐Layered Carbon Nitride Nanosheets with Enhanced Photocatalytic Hydrogen Evolution

Advanced Functional Materials, EarlyView.
A solvent‐free mechanochemistry‐enabled supramolecular engineering strategy is developed to directly synthesize covalent‐interconnected two‐dimensional atomic‐layered carbon nitride nanosheets photocatalyst, bypassing conventional top‐down exfoliation requirements.
Fanglei Yao, Jingwen Sun, Huiru Duan, Yongsheng Fu, Jin Wang, Liming Dai, Jingsan Xu, Junwu Zhu   +7 more
wiley   +1 more source

Complement C3 Affects Rac1 Activity in the Developing Brain

Frontiers in Molecular Neuroscience, 2018
The complement system, which is part of the innate immune response system, has been recently shown to participate in multiple key processes in the developing brain.
Anna Gorelik, T. Sapir, Lihi Ben-Reuven, O. Reiner   +3 more
semanticscholar   +1 more source

Genetic analysis of the complement pathway in C3 glomerulopathy [PDF]

Nephrology Dialysis Transplantation, 2018
C3 glomerulopathy often presents with a membranoproliferative glomerulonephritis (MPGN) pattern, and is principally caused by unrestricted activation of the complement alternative pathway. Genetic abnormalities of the complement system critically implicate in the pathogenesis of C3 glomerulopathy, but a systemic profile remains open, especially in Asia.
Yin Ding, Yin Ding, Caihong Zeng, Zhihong Liu, Zhihong Liu, Tao Zhang, Dacheng Chen, Wei-Wei Zhao, Jianping Lu, Jianping Lu, Huimei Chen, Haitao Zhang   +11 more
openaire   +3 more sources

Functional Materials for Environmental Energy Harvesting in Smart Agriculture via Triboelectric Nanogenerators

Advanced Functional Materials, EarlyView.
This review explores functional and responsive materials for triboelectric nanogenerators (TENGs) in sustainable smart agriculture. It examines how particulate contamination and dirt affect charge transfer and efficiency. Environmental challenges and strategies to enhance durability and responsiveness are outlined, including active functional layers ...
Rafael R. A. Silva, Giulio Fatti, Emanuel Carlos, Guilherme Ferreira, Sumita Goswami, Suman Nandy, Luiz H. C. Mattoso, Elvira Fortunato, Caio G. Otoni, Rodrigo Martins   +9 more
wiley   +1 more source

C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulation

Frontiers in Nephrology
C3 glomerulopathy (C3G) is an ultra-rare complement-mediated kidney disease caused by to the deregulation of the alternative pathway (AP) of proximal complement.
Karin Heidenreich, Deepti Goel, P. S. Priyamvada, Sagar Kulkarni, Vipul Chakurkar, Dinesh Khullar, Ravi Singh, Charan Bale, Peter F. Zipfel   +8 more
doaj   +1 more source

Mutations in complement C3 from aHUS patients [PDF]

Blood, 2015
In this issue of Blood, Schramm et al demonstrate that the majority of mutations in complement C3 identified in atypical hemolytic uremic syndrome (aHUS) patients cause dysregulation in the alternative pathway of complement.
openaire   +4 more sources