Results 131 to 140 of about 158,014 (317)

Lactate Dehydrogenase C4 Accelerates Triple‐Negative Breast Cancer Progression by Promoting Acetyl‐CoA Acyltransferase 2 Lactylation to Increase Free Fatty Acid Accumulation

Advanced Science, EarlyView.
Diagram of the reprogramming of FA metabolism mediated by LDHC4‐induced ACAA2 activity to promote TNBC progression. LDHC4 drives TNBC progression by enhancing ACAA2‐mediated fatty acid production. The resulting accumulation of FFAs stimulates autophagy and accelerates cell cycle progression, thereby promoting tumor growth.
Zhaolei Cui, Chaoqiang Zheng, Yingying Lin, Zhenzhou Xiao, Yanhong Li, Wei Peng, Shijie He, Anyang Li, Xiufeng Wu, Yan Chen, Yang Sun   +10 more
wiley   +1 more source

Complement C4-A and Plasminogen as Potential Biomarkers for Prediction of Papillary Thyroid Carcinoma. [PDF]

Front Endocrinol (Lausanne), 2021
Wang Y, Zhou S, Wang D, Wei T, Zhu J, Li Z.   +5 more
europepmc   +1 more source

Studies of α′,β′‐Epoxyketone Synthesis by Small‐Molecule Flavins and Flavoenzymes

Angewandte Chemie, EarlyView.
A combined synthetic and biochemical approach links the flavoenzyme EpxF to three key steps in epoxomicin biosynthesis. Crystallography, mutagenesis, and 13C‐labeling complete the mechanistic picture of α′,β′‐epoxyketone formation and illustrate the potential of flavin‐mediated transformations.
Alexandra Walter, Wolfgang Kuttenlochner, Wolfgang Eisenreich, Chengyang Yao, Michael Groll, Golo Storch   +5 more
wiley   +2 more sources

Use of a cDNA clone for the fourth component of human complement (C4) for analysis of a genetic deficiency of C4 in guinea pig. [PDF]

, 1983
Alexander S. Whitehead, Gabriel Goldberger, D E Woods, Alexander F. Markham, Harvey R. Colten   +4 more
openalex   +1 more source

Solving Triangular Peg Solitaire

, 2007
We consider the one-person game of peg solitaire on a triangular board of arbitrary size. The basic game begins from a full board with one peg missing and finishes with one peg at a specified board location. We develop necessary and sufficient conditions
Bell, George I.
core   +6 more sources

On the Design of Effective Water‐Soluble Actinide‐Masking Ligands Through Ligand Structure Modulation

Advanced Science, EarlyView.
Ligand topology and non‐coordination atoms are proved to be important for the design of effective water‐soluble actinide masking agents. Abstract Water‐soluble actinide‐masking ligands are fundamentally important for achieving efficient lanthanide/actinide separation and for the development of water‐soluble f‐block complexes for bioimaging and ...
Bin Li, Yu Kang, Ziyi Zhang, Ludi Wang, Haoyu Li, Yuxiao Guo, Guo Wang, Li Wang, Xiaoyan Tang, Chao Xu   +9 more
wiley   +1 more source

Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases. [PDF]

Arthritis Rheumatol, 2022
Lundtoft C, Pucholt P, Martin M, Bianchi M, Lundström E, Eloranta ML, Sandling JK, Sjöwall C, Jönsen A, Gunnarsson I, Rantapää-Dahlqvist S, Bengtsson AA, Leonard D, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Magnusson Bucher S, Norheim KB, Auglaend Johnsen SJ, Omdal R, Kvarnström M, Wahren-Herlenius M, Notarnicola A, Andersson H, Molberg Ø, Diederichsen LP, Almlöf J, Syvänen AC, Kozyrev SV, Lindblad-Toh K, DISSECT Consortium, ImmunoArray Development Consortium, Nilsson B, Blom AM, Lundberg IE, Nordmark G, Diaz-Gallo LM, Svenungsson E, Rönnblom L.   +41 more
europepmc   +1 more source

Synthesis and Application of Bioactive N‐Functionalized Aziridines

Angewandte Chemie, EarlyView.
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan, Samya Samanta, Nan Qiu, Alexander Adibekian, David C. Powers   +4 more
wiley   +2 more sources

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA. [PDF]

, 1984
R T Ogata, Diane S. Sepich
openalex   +1 more source

Anion‐Blocking and Multipath‐Conducting Interfaces Enable Long‐Life Room‐Temperature Ester‐Based Ca‐Metal Batteries

Advanced Science, EarlyView.
Long‐life pure calcium salt ester‐based Ca‐metal batteries of >500 cycles and 85.4% capacity retention at 25 mA g−1 are demonstrated by the Ca‐metal anodes with engineered interfaces, which featured not only diverse interphases of Ca‐/Fe‐based inorganic salts and core‐shell Fe nanocrystals affording abundant multiple ion/electron transportation ...
Xuedong He, Jiarui Wang, Qingyang Cao, Yaohua Huang, Hongqing Li, Fei Tian, Huawei Song, Chengxin Wang   +7 more
wiley   +1 more source