Results 161 to 170 of about 905,894 (352)

Harnessing Machine Learning to Enhance Transition State Search with Interatomic Potentials and Generative Models

open access: yesAdvanced Science, EarlyView.
Comprehensive evaluation of MLIPs and generative models for TS search using an end‐to‐end benchmark platform. Success rates, TS quality, and barrier prediction errors are systematically compared across models. The results reveal key performance trade‐offs and provide actionable insights for improving ML‐based transition state search and reaction ...
Qiyuan Zhao   +9 more
wiley   +1 more source

The Evaluation of the Level of C3 and C4 Complements in Unstimulated Saliva of Patients with Oral Lichen Planus

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2020
Background and Objectives: Deficiency in the complement system can lead to some autoimmune diseases, such as systemic lupus erythematosus. The purpose of this study was to investigate the levels of C3 and C4 complements in unstimulated saliva of ...
Bita Rohani   +2 more
doaj  

Engineering Adenine Deaminase TadA for Precise and PAM‐Flexible Point Mutagenesis and Gradient‐Tuning Endogenous Protein Design

open access: yesAdvanced Science, EarlyView.
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun   +14 more
wiley   +1 more source

Solving Triangular Peg Solitaire

open access: yes, 2007
We consider the one-person game of peg solitaire on a triangular board of arbitrary size. The basic game begins from a full board with one peg missing and finishes with one peg at a specified board location. We develop necessary and sufficient conditions
Bell, George I.
core   +6 more sources

Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions

open access: yesAngewandte Chemie, EarlyView.
In this study, we capitalize on the versatility offered by genetic code expansion to develop a proficient photoenzyme for [2 + 2]‐cycloadditions that is enantiocomplementary to our recently developed photoenzyme EnT1.3. By repositioning the genetically programmed benzophenone photosensitizer and subsequent directed evolution, we have developed an ...
Chuanjie Sun   +9 more
wiley   +2 more sources

Sequence comparison of alleles of the fourth component of complement (C4) andsex-limitedprotein (Slp) [PDF]

open access: green, 1986
Cynthia Hemenway   +4 more
openalex   +1 more source

A Strategic Approach for Enhanced p‐Type Doping of WSe2 p‐MOSFETs Using an Atomic Oxidation Process

open access: yesAdvanced Electronic Materials, EarlyView.
A robust approach to p‐type doping in monolayer WSe2 is demonstrated using phase‐engineered WSeyOx / WSe2 / WSeyOx heterostructures formed via atomic oxidation. Self‐limited surface oxidation enables non‐destructive charge transfer doping while preserving intrinsic channel properties.
Dongjea Seo   +10 more
wiley   +1 more source

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