Results 101 to 110 of about 675,301 (233)

Exploring Anticancer Activity and DNA Binding of Metal (II) Salicylaldehyde Schiff Base Complexes: A Convergence of Experimental and Computational Perspectives

Applied Organometallic Chemistry, Volume 39, Issue 5, May 2025.
This study synthesized four metal complexes of Co (II), Ni (II), Cu (II) and Pd (II) (C1‐C4), derived from salicylaldehyde‐based Schiff base. Through series of characterization, computational study and in vitro experiments, it has been demonstrated that C2 has a potential against breast cancer cell lines (MCF‐7).
Ibrahim Waziri, Sheldon Sookai, Tunde L. Yusuf, Kolawole A. Olofinsan, Alfred J. Muller   +4 more
wiley   +1 more source

Complement System in the Pathogenesis of Benign Lymphoepithelial Lesions of the Lacrimal Gland. [PDF]

PLoS ONE, 2016
We aimed to examine the potential involvement of local complement system gene expression in the pathogenesis of benign lymphoepithelial lesions (BLEL) of the lacrimal gland.We collected data from 9 consecutive pathologically confirmed patients with BLEL ...
Jing Li, Xin Ge, Xiaona Wang, Xiao Liu, Jianmin Ma   +4 more
doaj   +1 more source

NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3‐c][1,2]benzothiazine 5,5‐Dioxide Derivatives

Archiv der Pharmazie, Volume 358, Issue 5, May 2025.
The pyrazolo[4,3‐c][1,2]benzothiazine 5,5‐dioxide class was investigated with the aim of enlarging the array of Staphylococcus aureus NorA efflux pump inhibitors. The ethidium bromide efflux assay was used as a first indication of NorA inhibition; then, the ability of compounds to synergize with ciprofloxacin (CPX) against both wild‐type and resistant ...
Giada Cernicchi, Alessandra Di Gregorio, Tommaso Felicetti, Elisa Rampacci, Giulia Casari, Tatiana Armeni, Brenda Romaldi, Ermelinda Zefaj, Fabrizio Passamonti, Serena Massari, Giuseppe Manfroni, Maria Letizia Barreca, Oriana Tabarrini, Carla Vignaroli, Stefano Sabatini   +14 more
wiley   +1 more source

Unraveling the Genetic and Environmental Risk Factors of Autism Spectrum Disorder Through a Case‐Control Study in Armenia

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Autism spectrum disorder (ASD) is influenced by genetic and environmental factors. This study investigates genetic mutations and prenatal factors associated with ASD, including their interplay, in a multicenter case‐control study. Methods The study included 297 participants (149 ASD cases, 148 controls).
Meri Mkhitaryan, Tamara Avetisyan, Hermine Yeritsyan, Hayk Harutyunyan, Konstantin Yenkoyan   +4 more
wiley   +1 more source

Accuracy of a method based on atomic absorption spectrometry to determine inorganic arsenic in food : Outcome of the collaborative trial IMEP-41 [PDF]

, 2016
Peer reviewedPublisher ...
Cordeiro, F., Cubadda, F., de la Calle, M.B., Devesa, V., D’Amato, M., Emteborg, H., Feldmann, J., Fiamegkos, I., Llorente-Mirandes, T., Lopez-Sanchez, J.F., Raab, A., Raber, G., Rasmussen, R.R., Robouch, P., Rubio, R., Sloth, J.J., Vélez, D.   +16 more
core   +2 more sources

Can Labs Help With Vaccination? In Vitro Tests in Diagnosis of Allergy to COVID‐19 Vaccines–A Systematic Review

Immunity, Inflammation and Disease, Volume 13, Issue 5, May 2025.
The article describes novel approach to COVID‐19 allergy diagnosis protocols. To date most of them revolved around In Vivo tests (skin testing, provocations). We describe and propose implementation of In Vitro tests in allergy work‐up for those patients.
Jan Romantowski, Marika Gawinowska, Piotr Trzonkowski, Marek Niedoszytko   +3 more
wiley   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H., Mitchell, Daniel A., Schmid, Ralf, Schwaeble, Wilhelm J., Wallis, Russell   +4 more
core   +1 more source

Complement anaphylatoxin C4a inhibits C5a-induced neointima formation following arterial injury

Molecular Medicine Reports, 2014
Interactions between complement anaphylatoxins have been investigated in numerous fields; however, their functions during arterial remodeling following injury have not been studied. The inhibitory effect of complement anaphylatoxin C4a on neointima formation induced by C5a following arterial injury was investigated.
Bao-Dong Xie, Heng Xu, Yan Zhao, Wenhui Yu   +3 more
openaire   +4 more sources

Age-Related Maculopathy Susceptibility 2 and Complement Factor H Polymorphism and Intraocular Complement Activation in Neovascular Age-Related Macular Degeneration

Ophthalmology Science, 2022
Purpose: To investigate the association of risk alleles in complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) with complement activation products in the aqueous humor in eyes with neovascular age-related macular degeneration ...
Yutaka Kato, MD, Yasuharu Oguchi, MD, PhD, Tomoko Omori, PhD, Akihito Kasai, MD, Masashi Ogasawara, MD, Yukinori Sugano, MD, PhD, Kanako Itagaki, MD, Akira Ojima, MD, PhD, Yumi Ishida, Takeshi Machida, PhD, Hideharu Sekine, MD, PhD, Tetsuju Sekiryu, MD, PhD   +11 more
doaj  

The Aging Substantia Nigra is Characterized by ROS Accumulation Potentially Resulting in Increased Neuroinflammation and Cytoskeletal Remodeling

Advanced Biology, Volume 9, Issue 4, April 2025.
Definition of study groups, including young individuals (n = 7 mean age: 28.7 years), middle aged individuals (n = 14 mean age: 62.3 years) and elderly individuals (n = 14 mean age: 83.9 years). Condensed workflow including sample preparation (sample lysis and tryptic digestion), mass spectrometric measurements and subsequent data and statistical ...
Britta Eggers, Simone Steinbach, Isabel Gil Aldea, Sharon Keers, Mariana Molina, Lea T. Grinberg, Helmut Heinsen, Renata E. Paraizo Leite, Johannes Attems, Caroline May, Katrin Marcus   +10 more
wiley   +1 more source