Results 101 to 110 of about 11,949 (217)
OBJETIVO: determinar se os alótipos do Fator B (BF), C2 e C4 (C4A e C4B) do sistema complemento poderiam ser marcadores para a doença cardíaca reumática (DCR) na população brasileira. MÉTODOS: foram estudados 49 pacientes com DCR crônica.
Iara Jose de Messias-Reason +2 more
doaj +1 more source
Natural antibodies and CRP drive anaphylatoxin production by urate crystals
In gout, crystallization of uric acid in the form of monosodium urate (MSU) leads to a painful inflammatory response. MSU crystals induce inflammation by activating the complement system and various immune cell types, and by inducing necrotic cell death.
Anne Kathrin Wessig +7 more
doaj +1 more source
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Xavier Langon +2 more
wiley +1 more source
Serum proteomic analysis uncovers novel serum biomarkers for depression
ObjectiveThe identification of depression primarily relies on the clinical symptoms and psychiatric evaluation of the patient, in the absence of objective and quantifiable biomarkers within clinical settings.
Aihong Guo +12 more
doaj +1 more source
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann +2 more
wiley +1 more source
Genome-wide gene expression profiling of stress response in a spinal cord clip compression injury model. [PDF]
BackgroundThe aneurysm clip impact-compression model of spinal cord injury (SCI) is a standard injury model in animals that closely mimics the primary mechanism of most human injuries: acute impact and persisting compression.
Boutros, Paul C +5 more
core +3 more sources
Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by synaptic loss, as a key pathological feature in its early stages. Recent studies have highlighted the central role of microglia–complement interactions in synaptic pruning.
Qiuyan Ye +10 more
wiley +1 more source
Lewis meets Brouwer: constructive strict implication
C. I. Lewis invented modern modal logic as a theory of "strict implication". Over the classical propositional calculus one can as well work with the unary box connective.
Litak, Tadeusz, Visser, Albert
core +1 more source
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco +6 more
wiley +1 more source
Infektív, genetikai és complement aktivációs tényezők szerepének vizsgálata az autoimmun betegségek patogenezisében = Investigation of the role of infective, genetic and complement activation factor in the pathogenesis of autoimmune disorders [PDF]
Az MBL2 gén polimorfizmusa az SLE kialakulásának rizikó faktora. 315 SLE-s betegben és 182 kontrollban az MBL2 polimorfizmust vizsgáltuk. Kimutattuk, hogy az MBL2 polimorfizmusában a homozigóta SLE-s betegekben szignifikánsan fiatalabb életkorban (p=0 ...
Backhauszné dr. Takács, Edit Katalin +7 more
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