Results 91 to 100 of about 389,834 (185)

Complement system in dermatological diseases – fire under the skin

Frontiers in Medicine, 2015
The complement system plays a key role in several dermatological diseases. Overactivation, deficiency or abnormality of the control proteins are often related to a skin disease.
Jaana Helena Panelius, Jaana Helena Panelius, Seppo Kalevi Meri, Seppo Kalevi Meri, Seppo Kalevi Meri   +4 more
doaj   +1 more source

MALDI-TOF-MS Analysis in the Identification of Urine Proteomic Patterns of Gestational Trophoblastic Disease

Metabolites, 2019
Gestational trophoblastic disease (GTD) is a group of highly aggressive, rare tumors. Human chorionic gonadotropin is a common biomarker used in the diagnosis and monitoring of GTD.
Paulina Banach, Paweł Dereziński, Eliza Matuszewska, Jan Matysiak, Hubert Bochyński, Zenon J. Kokot, Ewa Nowak-Markwitz   +6 more
doaj   +1 more source

The Role of Complement in Tumors

, 2020
The complement system is an essential part of the innate immune system that is responsible for regulating inflammation, facilitating immune defense mechanisms, and maintaining tissue homeostasis.

core   +1 more source

Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1 beta

, 2010
Nijs J, Van Oosterwijck J, Meeus M, Lambrecht L, Metzger K, Fremont M, Paul L (Vrije Universiteit Brussel, Brussels; University College Antwerp, Antwerp; University Hospital Brussels, Brussels; Private Practice for Internal Medicine, Gent/Aalst; and RED ...
Van Oosterwijck, J., Metzger, K., Frémont, Marc, Paul, Lorna, Nijs, J., Nijs, Jo, Fremont, M., Paul, L.; id_orcid, Oosterwijck, J. Van, Meeus, M., Lambrecht, L., Metzger, Kristin, Paul, L., Meeus, Mira, Van Oosterwijck, Jessica, Lambrecht, Luc   +15 more
core   +1 more source

VISUAL PATTERNS OF С4А AND C4B SUBISOTYPES OF C4 COMPONENT OF HUMAN COMPLEMENT SYSTEM IN THE DIAGNOSTICS OF AUTOIMMUNE AND INFECTIOUS DISEASES

Acta Biomedica Scientifica, 2015
Results on visual patterns of subisotypes of patient sera complement component C4 complexes separated by isoelectric focusing in polyacrylamide gel and eiectrobiotting are presented.
M. V. Lakhtin, V. M. Lakhtin, S. S. Afanasiev, V. A. Aleshkin   +3 more
doaj  

Complement Cascades and Brain Disorders

Biomolecules
The complement system is a vital component of innate immunity. Besides its roles in pathogen defense, its significance in neurodevelopment, neurodegeneration, and cancer progression is beginning to be recognized.
Ivana Jovčevska, Alja Videtič Paska, Katarina Kouter   +2 more
doaj   +1 more source

Biosynthesis of complement C4 messenger RNA in normal human kidney [PDF]

, 1989
Feucht, Helmut E., Zwirner, Jörg, Felber, E., Lang, M., Bevec, Dorian, Weiss, Elisabeth H., Riethmüller, Gert   +6 more
core   +1 more source

Distinct effects of complement C4A and C4B copy number in Systemic Sclerosis serological and clinical subtypes

OBJECTIVE: Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes.
Mayes, Maureen D, Australian Scleroderma Interest Group (ASIG), ., Hunzelmann, Nicolas, Allanore, Yannick, Callejas, José L, Simeón-Aznar, Carmen P, Distler, Oliver, Nikpour, Mandana, Assassi, Shervin, Martin, Javier, Kerick, Martin, Guillen-Del-Castillo, Alfredo, Acosta-Herrera, Marialbert, de Vries-Bouwstra, Jeska K, Rangel-Peláez, Carlos, Denton, Christopher P, Alarcon-Riquelme, Marta E, Rodriguez-Martin, Inmaculada, Beretta, Lorenzo, Martínez-López, Javier, Proudman, Susanna M, Moroncini, Gianluca, International SSc Group; PRECISESADs Clinical Consortium, ., Herrick, Ariane L   +23 more
core   +1 more source

Complement Factor H: solution structures and interactions with ligands [PDF]

, 2009
Factor H (FH) is a plasma glycoprotein that plays a central role in regulating the alternative pathway of complement. It is composed of 20 short complement regulator (SCR) domains.
Okemefuna, A.I.
core  

Quantitation of C4a and C4b in systemic lupus erythematosus patients

, 1989
The fourth component of human complement (C4) exists in blood as two major forms or isotypes which differ in their biochemical and functional properties. Because C4A preferentially transacylates onto amino groups, it has been postulated that this isotype
Moulds, JoAnn Mary
core   +1 more source