Results 101 to 110 of about 11,655 (197)

Sample processing time but not storage time affects complement activation markers C4a, C4d, C3a, iC3b, Bb, C5a, and sC5b-9 levels in EDTA-plasma of individuals at clinical high-risk for psychosis

Biomarkers in Neuropsychiatry
The complement system is an important part of the innate immune system and plays a key role in inflammatory processes. Concentrations of complement activation fragments in plasma are markers of systemic activation and have been found to be altered in a ...
Eleftheria Kodosaki, Colm Healy, Jonah F. Byrne, Melanie Föcking, Mary Cannon, Diana O. Perkins, David Cotter, Meike Heurich   +7 more
doaj   +1 more source

Association Study of the Complement Component C4 Gene in Tardive Dyskinesia

Frontiers in Pharmacology, 2019
Tardive dyskinesia (TD) is a movement disorder that may develop in schizophrenia patients being treated long-term with antipsychotic medication. TD interferes with voluntary movements and leads to stigma, and can be associated with treatment non ...
Clement C. Zai, Clement C. Zai, Clement C. Zai, Clement C. Zai, Arun K. Tiwari, Arun K. Tiwari, Gwyneth C. Zai, Gwyneth C. Zai, Gwyneth C. Zai, Natalie Freeman, Jennie G. Pouget, Jennie G. Pouget, James Greco, Maria Tampakeras, Sajid A. Shaikh, Deanna Herbert, Heather Emmerson, Sheraz Y. Cheema, Nicole Braganza, Daniel J. Müller, Daniel J. Müller, Daniel J. Müller, Aristotle N. Voineskos, Aristotle N. Voineskos, Aristotle N. Voineskos, Gary Remington, Gary Remington, Gary Remington, James L. Kennedy, James L. Kennedy, James L. Kennedy   +30 more
doaj   +1 more source

Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice. [PDF]

Nat Neurosci, 2021
Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC.   +8 more
europepmc   +1 more source

Computationally Tractable Algorithms for Finding a Subset of Non-defective Items from a Large Population

, 2016
In the classical non-adaptive group testing setup, pools of items are tested together, and the main goal of a recovery algorithm is to identify the "complete defective set" given the outcomes of different group tests. In contrast, the main goal of a "non-
Murthy, Chandra R., Sharma, Abhay
core   +1 more source

Complement anaphylatoxin C4a inhibits C5a-induced neointima formation following arterial injury

Molecular Medicine Reports, 2014
Interactions between complement anaphylatoxins have been investigated in numerous fields; however, their functions during arterial remodeling following injury have not been studied. The inhibitory effect of complement anaphylatoxin C4a on neointima formation induced by C5a following arterial injury was investigated.
ZHAO, YAN, XU, HENG, YU, WENHUI, XIE, BAO-DONG   +3 more
openaire   +3 more sources

MALDI-TOF-MS Analysis in the Identification of Urine Proteomic Patterns of Gestational Trophoblastic Disease

Metabolites, 2019
Gestational trophoblastic disease (GTD) is a group of highly aggressive, rare tumors. Human chorionic gonadotropin is a common biomarker used in the diagnosis and monitoring of GTD.
Paulina Banach, Paweł Dereziński, Eliza Matuszewska, Jan Matysiak, Hubert Bochyński, Zenon J. Kokot, Ewa Nowak-Markwitz   +6 more
doaj   +1 more source

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

Nature Communications
Progressive supranuclear palsy (PSP), a rare Parkinsonian disorder, is characterized by problems with movement, balance, and cognition. PSP differs from Alzheimer’s disease (AD) and other diseases, displaying abnormal microtubule-associated protein tau ...
Kurt Farrell, Jack Humphrey, Timothy Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa, Vishakha Patil, Wan-Ping Lee, Amanda B. Kuzma, Otto Valladares, Laura B. Cantwell, Hui Wang, Ashvin Ravi, Claudia De Sanctis, Natalia Han, Thomas D. Christie, Robina Afzal, Shrishtee Kandoi, Kristen Whitney, Margaret M. Krassner, Hadley Ressler, SoongHo Kim, Diana Dangoor, Megan A. Iida, Alicia Casella, Ruth H. Walker, Melissa J. Nirenberg, Alan E. Renton, Bergan Babrowicz, Giovanni Coppola, Towfique Raj, Günter U. Höglinger, Ulrich Müller, Lawrence I. Golbe, Huw R. Morris, John Hardy, Tamas Revesz, Tom T. Warner, Zane Jaunmuktane, Kin Y. Mok, Rosa Rademakers, Dennis W. Dickson, Owen A. Ross, Li-San Wang, Alison Goate, Gerard Schellenberg, Daniel H. Geschwind, PSP Genetics Study Group, John F. Crary, Adam Naj   +49 more
doaj   +1 more source

Correction: Copy Number Analysis of Complement C4A, C4B and C4A Silencing Mutation by Real-Time Quantitative Polymerase Chain Reaction

PLoS ONE, 2012
There was an error in the Competing Interests statement. The correct Competing interests are: MLL is working as a consultant at a company owned by the University of Helsinki providing complement C4 analysis for diagnostic samples. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. The other authors
Paakkanen, Riitta, Vauhkonen, Hanna, Eronen, Katja T., Järvinen, Asko, Seppänen, Mikko, Lokki, Marja-Liisa   +5 more
doaj   +4 more sources

Infektív, genetikai és complement aktivációs tényezők szerepének vizsgálata az autoimmun betegségek patogenezisében = Investigation of the role of infective, genetic and complement activation factor in the pathogenesis of autoimmune disorders [PDF]

, 2008
Az MBL2 gén polimorfizmusa az SLE kialakulásának rizikó faktora. 315 SLE-s betegben és 182 kontrollban az MBL2 polimorfizmust vizsgáltuk. Kimutattuk, hogy az MBL2 polimorfizmusában a homozigóta SLE-s betegekben szignifikánsan fiatalabb életkorban (p=0 ...
Backhauszné dr. Takács, Edit Katalin, Farkas, Henriette, Fekete, Béla, Jakab, László, Kalabay, László, Pozsonyi, Teréz, Temesszentandrási, György, Varga, Lilian Ágnes   +7 more
core  

VISUAL PATTERNS OF С4А AND C4B SUBISOTYPES OF C4 COMPONENT OF HUMAN COMPLEMENT SYSTEM IN THE DIAGNOSTICS OF AUTOIMMUNE AND INFECTIOUS DISEASES

Acta Biomedica Scientifica, 2015
Results on visual patterns of subisotypes of patient sera complement component C4 complexes separated by isoelectric focusing in polyacrylamide gel and eiectrobiotting are presented.
M. V. Lakhtin, V. M. Lakhtin, S. S. Afanasiev, V. A. Aleshkin   +3 more
doaj