: GL-2045 is a recombinant human immunoglobulin G1 (IgG1)–based Fc multimer designed to recapitulate the anti-inflammatory activities of intravenous immunoglobulin (IVIG) on the innate and adaptive immune responses. We used functional in vitro studies to
Hua Zhou+9 more
doaj
Covalent binding properties of the C4A and C4B isotypes of the fourth component of human complement on several C1-bearing cell surfaces. [PDF]
David E. Isenman, John R. Young
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Problems on electrorheological fluid flows
We develop a model of an electrorheological fluid such that the fluid is considered as an anisotropic one with the viscosity depending on the second invariant of the rate of strain tensor, on the module of the vector of electric field strength, and on ...
Hoppe, R. H. W., Litvinov, W. G.
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Results on visual patterns of subisotypes of patient sera complement component C4 complexes separated by isoelectric focusing in polyacrylamide gel and eiectrobiotting are presented.
M. V. Lakhtin+3 more
doaj
Null alleles of human complement C4. Evidence for pseudogenes at the C4A locus and for gene conversion at the C4B locus. [PDF]
Lara Braun+4 more
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The complete exon-intron structure of a human complement component C4A gene. DNA sequences, polymorphism, and linkage to the 21-hydroxylase gene. [PDF]
C. Yung Yu
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Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima+18 more
core
Influence of functional deficiency of complement mannose-binding lectin on outcome of patients with acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention [PDF]
Aims Experimental data point towards a favourable effect of low serum concentrations of complement mannose-binding lectin (MBL) on myocardial ischaemia/reperfusion (I/R) injury.
Armstrong, Paul+5 more
core
Higher plasma levels of complement C3a, C4a and C5a increase the risk of subretinal fibrosis in neovascular age-related macular degeneration [PDF]
Judith Lechner+6 more
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