Results 161 to 170 of about 367,967 (298)

Complement factor B deficiency associated with recurrent asceptic meningitis [PDF]

Pediatric Rheumatology, 2008
Joke Dehoorne, Filomeen Haerynck, Ann Raes, J. Vande Walle, A. De Guchtenaere, Rik Joos   +5 more
openaire   +2 more sources

Performance of Composite Endpoints Defining Progression Independent of Relapse Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos, Sean Yiu, Jason Reucassel, Jiwon Oh, Cristina Granziera, Joep Killestein, Robert A. Bermel, Claude Berge, Agne Kazlauskaite, Hans‐Martin Schneble, Frank Dahlke, Bruce A. C. Cree   +11 more
wiley   +1 more source

Re: "The Association Between Complement Component 2/Complement Factor B Polymorphisms and Age-related Macular Degeneration: A Huge Review and Meta-analysis" [PDF]

, 2013
Sandra Tillmann, Andreas T. Grasskamp, Matthias Wulf, L Martis, Martina Domani, Philipp Sand   +5 more
openalex   +1 more source

Molecular Screening of SCN1A‐Related Seizures in Children With Febrile Seizures: Diagnostic Yield and Variant Distribution

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SCN1A‐related seizures first present as febrile seizures (FS). Definitive features emerge later, making early diagnosis challenging. We evaluated the diagnostic yield and clinical characteristics of pathogenic SCN1A variants in FS, and analyzed the effect of variant characteristics on clinical phenotypes required for early ...
Jia Wang, Yang‐Yang Wang, Lin‐Yan Hu, Xiu‐Yu Shi, Wen He, Dan Sun, Baoguang Li, Xiaoming Liu, Sanqing Xu, Lijun Du, Chunhui Tang, Li‐Ping Zou   +11 more
wiley   +1 more source

Role of complement factor B rs4151667 (L9H) polymorphisms and its interactional role with CFH Y402H and C3 rs2230199 (R102G) risk variants in age-related macular degeneration: a case control study. [PDF]

BMC Ophthalmol, 2020
Roshanipour N, Laleh MG, Bonyadi M, Bonyadi MHJ, Soheilian M, Javadzadeh A, Yaseri M.   +6 more
europepmc   +1 more source

Molecular Cloning of Apobec-1 Complementation Factor, a Novel RNA-Binding Protein Involved in the Editing of Apolipoprotein B mRNA

, 2000
Anuradha Mehta, Michael Kinter, Nicholas E. Sherman, Donna M. Driscoll   +3 more
openalex   +1 more source

High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li, Binbin Xue, Jia Li, Dewei Xie, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Xu Zhang, Junhui Xia, Jie Lin   +10 more
wiley   +1 more source

Complement factor B inhibitor LNP023 mediates the effect and mechanism of AMPK/mTOR on autophagy and oxidative stress in lupus nephritis. [PDF]

Kaohsiung J Med Sci
Zhang XM, Qing MJ, Liu XK, Peng L.
europepmc   +1 more source

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases [PDF]

, 2019
Anna Schubart, Karen Anderson, Nello Mainolfi, Holger Sellner, Takeru Ehara, Christopher M. Adams, Aengus Mac Sweeney, Sha-Mei Liao, Maura Crowley, Amanda Littlewood‐Evans, Sophie Sarret, Grazyna Wieczorek, Ludovic Perrot, Valérie Dubost, Thierry Flandre, Yuzhou Zhang, Richard J. Smith, Antonio M. Risitano, Rajeshri G. Karki, Chun Zhang, Eric Valeur, Finton Sirockin, Bernd Gerhartz, P. Erbel, Nicola Hughes, Thomas M. Smith, Frédéric Cumin, Upendra A. Argikar, Börje Haraldsson, Muneto Mogi, Richard Sedrani, Christian Wiesmann, Bruce Jaffee, Jürgen Maibaum, Stefanie Flohr, R. A. Harrison, Jörg Eder   +36 more
openalex   +1 more source

Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site

, 2021
Nathaniel Sands, Peter T. Beernink
openalex   +2 more sources