To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Functional Evaluation of AMD-Associated Risk Variants of Complement Factor B. [PDF]
Pilotti C, Greenwood J, Moss SE.
europepmc +1 more source
IL-17 regulates gene expression and protein synthesis of the complement system, C3 and factor B, in skin fibroblasts [PDF]
Yitzhak Katz +3 more
openalex +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
EVALUATION OF THE SERUM LEVELS OF IMMUNOGLOBULINS AND COMPLEMENT FACTORS IN B-THALASSEMIA MAJOR PATIENTS IN SOUTHERN IRAN [PDF]
Ahmad Amin +5 more
openalex
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A non-synonymous variant rs12614 of complement factor B associated with risk of chronic hepatitis B in a Korean population. [PDF]
Seo JY +8 more
europepmc +1 more source
Crystal Structure of the A Domain from Complement Factor B Reveals an Integrin-like Open Conformation [PDF]
Ananyo A. Bhattacharya +3 more
openalex +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source

