Results 11 to 20 of about 1,348,900 (304)

Complement factor B inhibitor LNP023 mediates the effect and mechanism of AMPK/mTOR on autophagy and oxidative stress in lupus nephritis. [PDF]

Kaohsiung J Med Sci
Zhang XM, Qing MJ, Liu XK, Peng L.
europepmc   +3 more sources

Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis. [PDF]

Front Immunol, 2020
Shinjyo N, Hikosaka K, Kido Y, Yoshida H, Norose K.   +4 more
europepmc   +3 more sources

Assessment of QT Interval Prolongation Using Concentration-QT Modeling for Iptacopan, an Oral Complement Factor B Inhibitor, in Healthy Individuals. [PDF]

Clin Transl Sci
Kaetterer N, Kulmatycki K, Nidamarthy PK, McNamara E, Armas D, Jarugula V, Schmouder R.   +6 more
europepmc   +3 more sources

Case Report: Combined Liver-Kidney Transplantation to Correct a Mutation in Complement Factor B in an Atypical Hemolytic Uremic Syndrome Patient. [PDF]

Front Immunol, 2021
López-Trascasa M, Alonso-Melgar Á, Melgosa-Hijosa M, Espinosa-Román L, Lledín-Barbancho MD, García-Fernández E, Rodríguez de Córdoba S, Sánchez-Corral P.   +7 more
europepmc   +2 more sources

The Ba fragment of complement factor B inhibits human B lymphocyte proliferation. [PDF]

The Journal of Immunology, 1990
Abstract Normal human B lymphocyte function is finely regulated by both positive and negative signals at each stage of activation, proliferation, and differentiation. Activation signals include antigen and surface Ig cross-linking agents such as anti-mu or anti-delta.
Julian L. Ambrus, M G Peters, A S Fauci, E J Brown   +3 more
openalex   +3 more sources

Complement factor B (CFB) [PDF]

Science-Business eXchange, 2009

openalex   +3 more sources

Complement factor B knockdown by short hairpin RNA inhibits laser-induced choroidal neovascularization in rats. [PDF]

Int J Ophthalmol, 2020
AIM: To evaluate whether recombinant complement factor B (CFB) short hairpin RNA (shRNA) reduces laser-induced choroidal neovascularization (CNV) in rats.
Wang X, Shang QL, Ma JX, Liu SX, Wang CX, Ma C.   +5 more
europepmc   +2 more sources

Interrelationship between Porphyromonas gingivalis and complement C3 and factor B Levels in chronic periodontitis individuals

Dentistry and Medical Research, 2019
Background: To evaluate the effect of nonsurgical periodontal therapy on gingival crevicular fluid (GCF) and serum levels of complement C3 and factor B and their correlation with Porphyromonas gingivalis levels in chronic periodontitis (CP) individuals ...
Srirangarajan Sridharan, P. Sravani
openalex   +3 more sources

Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis. [PDF]

Crit Care Med, 2016
Li D, Zou L, Feng Y, Xu G, Gong Y, Zhao G, Ouyang W, Thurman JM, Chao W.   +8 more
europepmc   +3 more sources

Factor H preserves alternative complement function during ARDS, linked to improved survival

ERJ Open Research, 2023
Background Effective regulation of complement activation may be crucial to preserving complement function during acute respiratory distress syndrome (ARDS). Factor H is the primary negative regulator of the alternative pathway of complement.
William Bain, Mohammadreza Tabary, Sara R. Moore, Xiaojing An, Georgios D. Kitsios, Bryan J. McVerry, Prabir Ray, Anuradha Ray, Rama K. Mallampalli, Viviana P. Ferreira, Janet S. Lee, S. Mehdi Nouraie   +11 more
doaj   +1 more source