Results 21 to 30 of about 367,967 (298)
A new complement factor B mutation associated with crescentic C3 glomerulopathy; a case report [PDF]
Journal of Nephropathology, 2019 Background: C3 glomerulopathy is a recently described entity classified as complementassociated glomerular disease. Case Presentation: We report a case of a 48-year-old man referred to the nephrology department for nephrotic syndrome with rapidly ...
Sofia Semedo Coelho +10 more
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The Bb fragment of complement factor B acts as a B cell growth factor. [PDF]
The Journal of experimental medicine, 1988 The process of B cell growth and differentiation into plasma cells is highly regulated and may be influenced by a large number of inflammatory mediators, including complement components. We have studied the regulatory influence of Bb, a 60-kD peptide created during the cleavage of complement Factor B by Factor D and C3b. Purified Bb alone had no effect
Peters, MG +3 more
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Complement Dysregulation in Obese Versus Nonobese Polycystic Ovary Syndrome Patients
Cells, 2023 Introduction: Upregulation of complement system factors are reported to be increased in polycystic ovary syndrome (PCOS) and may be due to obesity and insulin resistance rather than inherently due to PCOS.
Alexandra E. Butler +3 more
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Schizophrenia, 2023 Schizophrenia has been linked to polymorphism in genes encoding components of the complement system, and hyperactive complement activity has been linked to immune dysfunction in schizophrenia patients.
Hua Yu +13 more
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The alternative pathway of complement activation may be involved in the renal damage of human anti-glomerular basement membrane disease. [PDF]
PLoS ONE, 2014 Linear deposition of IgG and complement 3 (C3) along glomerular basement membrane (GBM) is generally revealed in the kidneys of human anti-GBM disease. Our recent studies demonstrated the pathogenic role of complement activation in renal damage of this ...
Rui Ma +9 more
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Frontiers in Microbiology, 2015 The virulence factor PgtE is an outer membrane protease (omptin) of the zoonotic pathogen Salmonella enterica that causes diseases ranging from gastroenteritis to severe enteric fever. It is surface exposed in bacteria that have a short-chain, i.e. rough
Rauna eRiva +2 more
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Characterization of the sheep Complement Factor B gene (CFB) [PDF]
Veterinary Immunology and Immunopathology, 2011 The Complement Factor B gene (CFB) of the alternative complement pathway has been identified in the sheep Major Histocompatibility Complex (MHC) and its genomic sequence determined. CFB is located approximately 600 bp upstream of the complement C2 gene, contains 18 exons, and manifests the domain signature characteristic of CFB protein. Thirteen single
Qin, J +4 more
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Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components. [PDF]
PLoS ONE, 2013 Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Jasmin Schwab +7 more
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Complement factor B mutation-associated aHUS and myocardial infarction. [PDF]
BMJ Case Rep, 2017 A 6-month-old female infant was referred with a 3-day history of low-grade fever, slight nasal congestion and rhinorrhoea. On admission, the clinical findings were unremarkable and she was discharged home. However, she became progressively more listless with a decreased urine output and was once again seen in the emergency department.
Noronha N, Costa FD, Dias A, Dinis A.
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Nomenclature for human complement factor B [PDF]
Journal of Immunological Methods, 1993 Abstract In this note is recommended a unified nomenclature for allotypes and variants of human complement factor B, which was approved by the Nomenclature Committee of the International Union of Immunological Societies (IUIS).
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