Results 21 to 30 of about 1,344,365 (268)

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex [PDF]

, 2016
Citation: Garcia, B. L., Zhi, H., Wager, B., Hook, M., & Skare, J. T. (2016). Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex. Plos Pathogens, 12(1), 28.
A Alitalo, A Hubner, A Roos, A Sadziene, A Sadziene, AE Davis 3rd, AG Barbour, AP van Dam, B Major, Beau Wager, BK Boardman, Brandon L. Garcia, BV Geisbrecht, C Gaboriaud, CA Brissette, CJ Hastey, CS Brooks, D Ricklin, D Ricklin, D. Scott Samuels, DS Samuels, E Fikrig, EA Rogers, EA Rogers, EH Weening, ER Lewis, G Harris, G Stanek, Girija U Venkatraman, H Zhi, Hui Zhi, I Bally, J Hellwage, J Pietikainen, J Schwab, J Seshu, JA Caine, JA Hyde, JD Lambris, JD Radolf, JH Kim, Jon T. Skare, JR Fischer, JV McDowell, JV McDowell, K Kurtenbach, KM Hovis, LK Bockenstedt, LY Lee, M Hammel, M He, M Jozsi, M Labandeira-Rey, M Pausa, Magnus Höök, MB Lawrenz, MC Carroll, MC Carroll, ME Woodman, MJ Caimano, MN Burtnick, MR Kenedy, MR Kenedy, MU Norman, NA Meenan, NM Thielens, P Kraiczy, P Kraiczy, PF Zipfel, R Wallis, RA Elsner, RA Gaultney, RJ Bingham, RJ Ziccardi, RJ Ziccardi, S Grosskinsky, S Prabhakaran, S Raibaud, S Thiel, SK Kochi, SW de Taeye, T Bykowski, T Hallstrom, T Hallstrom, T Meri, TF Busby, TJ Moriarty, U Schwarz-Linek, UK Laemmli, V Cook, WK Ip, WS Probert, WS Probert, WS Probert, X Li, X Yang, XF Yang, Y Wu, YP Ko, YP Ko, YP Lin, ZR Marjenberg   +101 more
core   +8 more sources

Nomenclature for human complement factor B [PDF]

Journal of Immunological Methods, 1993
Abstract In this note is recommended a unified nomenclature for allotypes and variants of human complement factor B, which was approved by the Nomenclature Committee of the International Union of Immunological Societies (IUIS).
openaire   +2 more sources

Association of elevated levels of peripheral complement components with cortical thinning and impaired logical memory in drug-naïve patients with first-episode schizophrenia

Schizophrenia, 2023
Schizophrenia has been linked to polymorphism in genes encoding components of the complement system, and hyperactive complement activity has been linked to immune dysfunction in schizophrenia patients.
Hua Yu, Peiyan Ni, Yang Tian, Liansheng Zhao, Mingli Li, Xiaojing Li, Wei Wei, Jinxue Wei, Qiang Wang, Wanjun Guo, Wei Deng, Xiaohong Ma, Jeremy Coid, Tao Li   +13 more
doaj   +1 more source

The outer membrane protease PgtE of Salmonella enterica interferes with the alternative complement pathway by cleaving factors B and H

Frontiers in Microbiology, 2015
The virulence factor PgtE is an outer membrane protease (omptin) of the zoonotic pathogen Salmonella enterica that causes diseases ranging from gastroenteritis to severe enteric fever. It is surface exposed in bacteria that have a short-chain, i.e. rough
Rauna eRiva, Timo K. Korhonen, Seppo eMeri   +2 more
doaj   +1 more source

The alternative pathway of complement activation may be involved in the renal damage of human anti-glomerular basement membrane disease. [PDF]

PLoS ONE, 2014
Linear deposition of IgG and complement 3 (C3) along glomerular basement membrane (GBM) is generally revealed in the kidneys of human anti-GBM disease. Our recent studies demonstrated the pathogenic role of complement activation in renal damage of this ...
Rui Ma, Zhao Cui, Shui-Yi Hu, Xiao-Yu Jia, Rui Yang, Xin Zheng, Jie Ao, Gang Liu, Yun-Hua Liao, Ming-Hui Zhao   +9 more
doaj   +1 more source

Anti-factor B autoantibody in dense deposit disease [PDF]

, 2010
Dense deposit disease (DDD), also known as membranoproliferative glomerulonephritis type II, is a rare kidney disorder that is associated with dysregulation of the alternative pathway of complement.
Józsi, Mihály, Papp, Krisztián, Prechl, József, Strobel, S., Zimmering, M.   +4 more
core   +1 more source

Characterization of the sheep Complement Factor B gene (CFB) [PDF]

Veterinary Immunology and Immunopathology, 2011
The Complement Factor B gene (CFB) of the alternative complement pathway has been identified in the sheep Major Histocompatibility Complex (MHC) and its genomic sequence determined. CFB is located approximately 600 bp upstream of the complement C2 gene, contains 18 exons, and manifests the domain signature characteristic of CFB protein. Thirteen single
Qin, J, Munyard, Kylie, Lee, C, Wetherall, John, Groth, David   +4 more
openaire   +3 more sources

Atypical hemolytic uremic syndrome : update on the complement system and what is new [PDF]

, 2010
Atypical hemolytic uremic syndrome (aHUS) is a rare disease of microangiopathic hemolytic anemia, thrombocytopenia, and predominant renal impairment. It is characterized by the absence of Shiga toxin-producing bacteria as a triggering factor.
Dickenmann, Michael, Hirt-Minkowski, Patricia, Schifferli, Jürg A.   +2 more
core   +1 more source

Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production

Frontiers in Immunology, 2019
Complement factor H (CFH) has a pivotal role in regulating alternative complement activation through its ability to inhibit the cleavage of the central complement component C3, which links innate and humoral immunity.
Máté G. Kiss, Máté G. Kiss, Mária Ozsvár-Kozma, Mária Ozsvár-Kozma, Florentina Porsch, Florentina Porsch, Laura Göderle, Laura Göderle, Nikolina Papac-Miličević, Nikolina Papac-Miličević, Barbara Bartolini-Gritti, Barbara Bartolini-Gritti, Dimitrios Tsiantoulas, Dimitrios Tsiantoulas, Matthew C. Pickering, Christoph J. Binder, Christoph J. Binder   +16 more
doaj   +1 more source

Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein [PDF]

, 2012
Human complement factor H-related protein (CFHR) 4 belongs to the factor H family of plasma glycoproteins that are composed of short consensus repeat (SCR) domains.
Hebecker, Mario, Józsi, Mihály
core   +1 more source