Results 201 to 210 of about 1,235,428 (322)

Inadequate Binding of Immune Regulator Factor H Is Associated with Sensitivity ofBorrelia lusitaniaeto Human Complement

, 2010
Roswitha Dieterich, Claudia Hammerschmidt, D. Richter, Christine Skerka, Reinhard Wallich, Franz‐Rainer Matuschka, Peter F. Zipfel, Peter Kraiczy   +7 more
openalex   +2 more sources

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 [PDF]

Ramada R. Khaswaneh, Ejlal Abu‐El‐Rub, Ayman Alzu’bi, Fatimah Almahasneh, Rawan A. Almazari, Heba F. AI-jariri, Raed M. Al‐Zoubi   +6 more
openalex   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Disease Progression in Age-Related Macular Degeneration Patients Carrying Rare Variants in the Complement Factor H or Complement Factor I Genes. [PDF]

Invest Ophthalmol Vis Sci
Cinque F, de Breuk A, Mhmud H, De Jong S, Vermeulen J, Liefers B, den Hollander AI, Thee E, Colijn JM, Heesterbeek TJ, Klaver CC, Hoyng CB, Lechanteur YTE.   +12 more
europepmc   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Fibrinogen and Complement Factor H Induce Parkinsonian and Cognitive Impairment-Like Features in Mice. [PDF]

Cell Mol Neurobiol
Naskar A, Sachin M, Sengupta S, Bhadrachalam P, Hegde S, Yadav R, Pal PK, Alladi PA.   +7 more
europepmc   +1 more source

AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model. [PDF]

Invest Ophthalmol Vis Sci, 2023
Grigsby D, Klingeborn M, Kelly U, Chew LA, Asokan A, Devlin G, Smith S, Keyes L, Timmers A, Scaria A, Bowes Rickman C.   +10 more
europepmc   +1 more source

Target complement factor H / serum amyloid a signaling in trichloroethylene-induced immune kidney injury

Haibo Xie, Bo Liang, Jingyi Zhao, You Chen, Qianming Bai, Rui Li, Jianmin Chen, Pengcheng Zhou, Luo-Lun Dong, Rui-Xuan Cheng, Jiaxiang Zhang, Qixing Zhu   +11 more
openalex   +1 more source

Upregulation of MicroRNA-146a by Hepatitis B Virus X Protein Contributes to Hepatitis Development by Downregulating Complement Factor H

, 2015
Junfeng Li, Xiaopeng Dai, Wei Zhang, Shihui Sun, Yang Zeng, Guangyu Zhao, Zhihua Kou, Yan Guo, Hong Yu, Lanying Du, Shibo Jiang, Yusen Zhou   +11 more
openalex   +1 more source