Results 201 to 210 of about 16,352,795 (292)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The Sialome of the Retina, Alteration in Age-Related Macular Degeneration Pathology, and Potential Impacts on Complement Factor H. [PDF]

Invest Ophthalmol Vis Sci
Swan J, Toomey CB, Bergstrand M, Cuello HA, Robie J, Yu H, Yuan Y, Kooner AS, Chen X, Shaughnessy J, Ram S, Varki A, Gagneux P.   +12 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Correction to 'The Impact of Complement Factor H-Related Protein Gene Deletions on Kidney Transplantation'. [PDF]

Scand J Immunol
europepmc   +1 more source

Complement Factor H Is an ICOS Ligand Modulating Tregs in the Glioma Microenvironment. [PDF]

Cancer Immunol Res
Smolag KI, Olszowka J, Rosberg R, Johansson E, Marinko E, Leandersson K, O'Connell DJ, Governa V, Tuysuz EC, Belting M, Pietras A, Martin M, Blom AM.   +12 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Serum Complement Factor H: A Marker for Progression and Outcome Prediction Towards Immunotherapy in Cutaneous Squamous Cell Carcinoma. [PDF]

Cancers (Basel)
Geidel G, Adam L, Bänsch S, Fekade N, Deitert B, Rünger A, Kött J, Zell T, Heidrich I, Smit DJ, Pantel K, Schneider SW, Gebhardt C.   +12 more
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Glycoproteomics analysis of complement factor H and its complement-regulatory function during <i>Streptococcus pneumoniae</i>-associated hemolytic uremic syndrome. [PDF]

Front Immunol
Baas LM, Wijnsma KL, Zijlstra F, van de Kar NCAJ, Ter Steeg L, Bouts AHM, Michels MAHM, Langereis JD, Lefeber D, Wessels HJCT, van den Heuvel LP.   +10 more
europepmc   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source