Results 211 to 220 of about 1,284,220 (297)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Anti-complement factor H (CFH) antibodies and a novel CFH gene mutation in an atypical hemolytic uremic syndrome patient with complement activation of the classical pathway

, 2021
Sonoko Minato, Hiroyuki Iijima, Hiro Nakao, Kentaro Nishi, Yoshihiko Hidaka, Norimitsu Inoue, Mitsuru Kubota, Akira Ishiguro   +7 more
openalex   +1 more source

Reviewer #2 (Public Review): Ocular biomarker profiling after complement factor I gene therapy in geographic atrophy secondary to age-related macular degeneration

Thomas M Hallam, Emanuela Gardenal, Fraser McBlane, GaEun Cho, Lucy Lee Ferraro, Eva Pekle, Darlene Lu, Kate Carney, Claire Wenden, Hannah Beadsmoore, Sergio Kaiser, Lauren Drage, Thomas Haye, Iris Kassem, Nalini Rangaswamy, Ma’en Obeidat, Cyndy Grosskreutz, Magali Saint-Geniez, David H Steel, Robert E MacLaren, on behalf of FOCUS Principal Investigators, Scott Ellis, Claire L Harris, Stephen Poor, Amy V Jones   +24 more
openalex   +1 more source

Elastase-alpha1-proteinase inhibitor complex [PDF]

, 1984
Bergmeyer, H. U., Bergmeyer, J., Graßl, M., Jochum, Marianne, Neumann, S.   +4 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Comprehensive functional characterization of complement factor I rare variant genotypes identified in the SCOPE geographic atrophy cohort. [PDF]

J Biol Chem
Hallam TM, Andreadi A, Sharp SJ, Brocklebank V, Gardenal E, Dreismann A, SCOPE Study Group, Lotery AJ, Marchbank KJ, Harris CL, Jones AV, Kavanagh D.   +11 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Primary pneumococcal peritonitis can be the first presentation of a familial complement factor I deficiency¹. [PDF]

Clin Exp Immunol, 2020
Ugrinovic S, Firth H, Kavanagh D, Gouliouris T, Gurugama P, Baxendale H, Lachmann PJ, Kumararatne D, Gkrania-Klotsas E.   +8 more
europepmc   +1 more source

The YeastCandida albicansBinds Complement Regulators Factor H and FHL-1

, 2002
Taru Meri, Andrea Hartmann, D. Lenk, Raimund Eck, Reinhard Würzner, Jens Hellwage, Seppo Meri, Peter F. Zipfel   +7 more
openalex   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source