Results 231 to 240 of about 2,740,548 (363)

Common variant rs10033900 near the complement factor I gene is associated with age-related macular degeneration risk in Han Chinese population [PDF]

, 2014
Ding-guo Qian, Mengyuan Kan, Xiaoling Weng, Yugeng Huang, Changbo Zhou, YU Gen-long, Ting Wang, Daizhan Zhou, Zhou Zhang, Di Zhang, Wei Tang, Yun Liu   +11 more
openalex   +1 more source

Variation near complement factor I is associated with risk of advanced AMD

European Journal of Human Genetics, 2009
J. Fagerness, J. Maller, B. Neale, Robyn C Reynolds, M. Daly, J. Seddon   +5 more
semanticscholar   +1 more source

CAMK2D and Complement Factor I-Involved Calcium/Calmodulin Signaling Modulates Sodium Iodate-Induced Mouse Retinal Degeneration. [PDF]

Invest Ophthalmol Vis Sci
Xu W, Cao L, Liu H.
europepmc   +1 more source

Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar, Ruo‐Yah Lai, Zena Fadel, Yicheng Lin, Pia Parekh, Rachel Griep, Ming‐Kai Pan, Sheng‐Han Kuo   +7 more
wiley   +1 more source

Both Complement- and Fibrinogen-Dependent Mechanisms Contribute to Platelet Aggregation Mediated by Staphylococcus aureus Clumping Factor B

, 2007
Helen Miajlović, Tony Loughman, Marian Brennan, Dermot Cox, Timothy J. Foster   +4 more
openalex   +1 more source

New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3 [PDF]

, 2014
Elizabeth Rodríguez, Pavithra M. Rallapalli, Amy J. Osborne, Stephen J. Perkins   +3 more
openalex   +1 more source

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source

Comprehensive functional characterization of complement factor I rare variant genotypes identified in the SCOPE geographic atrophy cohort. [PDF]

J Biol Chem
Hallam TM, Andreadi A, Sharp SJ, Brocklebank V, Gardenal E, Dreismann A, SCOPE Study Group, Lotery AJ, Marchbank KJ, Harris CL, Jones AV, Kavanagh D.   +11 more
europepmc   +1 more source

Primary pneumococcal peritonitis can be the first presentation of a familial complement factor I deficiency¹. [PDF]

Clin Exp Immunol, 2020
Ugrinovic S, Firth H, Kavanagh D, Gouliouris T, Gurugama P, Baxendale H, Lachmann PJ, Kumararatne D, Gkrania-Klotsas E.   +8 more
europepmc   +1 more source

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source