Results 61 to 70 of about 97,611 (303)

Attention gates visual coding in the human pulvinar. [PDF]

open access: yes, 2012
The pulvinar nucleus of the thalamus is suspected to have an important role in visual attention, based on its widespread connectivity with the visual cortex and the fronto-parietal attention network.
Fischer, Jason, Whitney, David
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Serological diagnosis of Q fever endocarditis [PDF]

open access: yes, 2017
The diagnosis of Q fever endocarditis cannot be made by bacterial cultures and necessitates serological identification of specific antibodies to Coxiella burnetii which stimulates mainly the production of anti-phase II antibodies during the acute diséase,
BURGDORFER, W.   +5 more
core  

Gaze-contingent flicker pupil perimetry detects scotomas in patients with cerebral visual impairments or glaucoma [PDF]

open access: yes, 2018
The pupillary light reflex is weaker for stimuli presented inside as compared to outside absolute scotomas. Pupillograph perimetry could thus be an objective measure of impaired visual processing.
Bergsma, Douwe P   +6 more
core   +3 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]

open access: yes, 2013
The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen   +6 more
core   +9 more sources

Bayesian Estimation of Sensitivity and Specificity of Rose Bengal, Complement Fixation, and Indirect ELISA Tests for the Diagnosis of Bovine Brucellosis in Ethiopia

open access: yesVeterinary Medicine International, 2016
Test evaluation in the absence of a gold standard test was conducted for the diagnosis and screening of bovine brucellosis using three commercially available tests including RBPT, CFT, and I-ELISA in National Animal Health Diagnostic and Investigation ...
T. Getachew   +4 more
doaj   +1 more source

Serological Survey of Bovine Brucellosis in Cameroon

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2005
A serological survey was carried out at the abattoir of Dschang (West Cameroon) from August 2002 to July 2003 in order to determine the prevalence of bovine brucellosis.
O. Shey-Njila   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Coccidiomycosis infection of the patella mimicking a neoplasm - two case reports. [PDF]

open access: yes, 2014
BackgroundCoccidioidomycosis is an endemic fungal infection in the southwestern of United States. Most infections are asymptomatic or manifest with mild respiratory complaints. Rare cases may cause extrapulmonary or disseminated disease.
Calvert, George   +4 more
core   +1 more source

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