Results 161 to 170 of about 96,307 (191)

Unraveling the Role of the Multifunctional Groups in the Adsorption of l-Cysteine on Rutile TiO<sub>2</sub>(110). [PDF]

open access: yesJ Am Chem Soc
Blanco Garcia M   +10 more
europepmc   +1 more source

Rare predicted loss-of-function and damaging missense variants in CFHR5 associate with protection from age-related macular degeneration. [PDF]

open access: yesAm J Hum Genet
Holleman AM   +11 more
europepmc   +1 more source

A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen. [PDF]

open access: yesBiochemistry
Peduzzi OM   +13 more
europepmc   +1 more source

Cyanate as an Inactivator of Complement Proteins

open access: closedThe Journal of Immunology, 1975
Abstract Sodium cyanate added to normal human serum or serum from patients with sickle-cell disease resulted in the functional inactivation of C3, C5, C6, C7, and the C3b inactivator, but not C8 and C9. Final concentrations as low as 0.5 mM in serum caused inactivation of 12 to 64% of the C3 after 8 hr at 37°C.
Duane R. Schultz, Patricia I. Arnold
semanticscholar   +4 more sources

Regulatory proteins for the activated third and fourth components of complement (C3b and C4b) in mice. I. Isolation and characterization of factor H: the serum cofactor for the C3b/C4b inactivator (Factor I)

open access: closedJournal of Immunological Methods, 1984
Factor H, purified from mouse EDTA-plasma using a 4-step procedure, consists of a single polypeptide chain of Mr 150,000 on SDS-PAGE. Mouse H (Hmo) was required for the cleavage of fluid-phase mouse C3b by mouse I (Imo). The final product of degradation of fluid-phase mouse C3b was iC3b, consisting of fragments of the alpha'-chain (alpha'-70, alpha'-43)
Taroh Kinoshita, Victor Nussenzweig
semanticscholar   +4 more sources

Limited Proteolysis of Complement Protein C3b by Regulatory Enzyme C3b Inactivator: Isolation and Characterization of a Biologically Active Fragment, C3d,g

open access: closedThe Journal of Biochemistry, 1985
Limited proteolysis of C3b by C3b inactivator (factor I) consists of a two-step reaction; rapid cleavage of C3b to yield a nicked C3b derivative, iC3b, and followed by slow cleavage of iC3b to yield two antigenically distinct fragments, C3c and C3d,g.
Tsukasa Seya, Shigeharu Nagasawa
openalex   +3 more sources

Complement inactivating proteins and intraspecies venom variation in Crotalus oreganus helleri

Toxicon, 2007
Complement inactivating properties were detected in venom from the southern California distribution of Crotalus oreganus helleri (Southern Pacific Rattlesnake). This activity showed strong geographic bias to the San Bernardino Mountain range, and venom from this area reacted strongly with Fraction 5 antiserum (AF5). However, venoms from the San Jacinto
Jennifer D, Jurado   +6 more
openaire   +2 more sources

Antibody-complement-mediated cytotoxicity is enhanced by ribosome-inactivating proteins.

The Journal of Immunology, 1985
Abstract The antibody-mediated cytotoxicity of complement can be increased by the ribosome-inactivating proteins gelonin and PAP-S. Treatment of human lymphoid cells that express CALLA with an anti-CALLA monoclonal antibody, J5, and then with rabbit complement, leaves about 6% of the cells alive.
V S, Goldmacher   +4 more
openaire   +2 more sources

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