Results 11 to 20 of about 3,236,190 (349)

Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity. [PDF]

Sci Rep, 2023
Diep NT, Giang NT, Diu NTT, Nam NM, Khanh LV, Quang HV, Hang NT, Mao CV, Son HV, Hieu NL, Linh PT, Sklan EH, Toan NL, Tong HV.   +13 more
europepmc   +3 more sources

Complement Receptor 3 Regulates Microglial Exosome Release and Related Neurotoxicity via NADPH Oxidase in Neuroinflammation Associated with Parkinson’s Disease [PDF]

Antioxidants (Basel)
Ma Y, Zhang X, Xu J, Luo R, Li S, Su H, Wang Q, Hou L.   +7 more
europepmc   +3 more sources

The complement receptor C5aR2 regulates neutrophil activation and function contributing to neutrophil-driven epidermolysis bullosa acquisita. [PDF]

Front Immunol, 2023
Seiler DL, Kähler KH, Kleingarn M, Sadik CD, Bieber K, Köhl J, Ludwig RJ, Karsten CM.   +7 more
europepmc   +2 more sources

Complement 5a Receptor Mediates Angiotensin II–Induced Cardiac Inflammation and Remodeling [PDF]

Arteriosclerosis, Thrombosis and Vascular Biology, 2014
Congcong Zhang, Yulin Li, Chunxiao Wang, Yi-na Wu, W. Cui, T. Miwa, Sayaka Sato, Hui-Hua Li, W. Song, Jie Du   +9 more
semanticscholar   +2 more sources

Aspects of the Complement System in New Era of Xenotransplantation

Frontiers in Immunology, 2022
After producing triple (Gal, H-D and Sda)-KO pigs, hyperacute rejection appeared to no longer be a problem. However, the origin of xeno-rejection continues to be a controversial topic, including small amounts of antibodies and subsequent activation of ...
Shuji Miyagawa, Shuji Miyagawa, Shuji Miyagawa, Akira Maeda, Chiyoshi Toyama, Shuhei Kogata, Chizu Okamatsu, Riho Yamamoto, Kazunori Masahata, Masafumi Kamiyama, Hiroshi Eguchi, Masahito Watanabe, Hiroshi Nagashima, Masahito Ikawa, Katsuyoshi Matsunami, Hiroomi Okuyama   +15 more
doaj   +1 more source

A Novel Image Analysis Approach Reveals a Role for Complement Receptors 1 and 2 in Follicular Dendritic Cell Organization in Germinal Centers

Frontiers in Immunology, 2021
Follicular dendritic cells (FDCs) are rare and enigmatic cells that mainly reside in germinal centers (GCs). They are capable of capturing immune complexes, via their Fc (FcRs) and complement receptors (CRs) and storing them for long periods in non ...
Jessica C. Anania, Annika Westin, Jeremy Adler, Birgitta Heyman   +3 more
doaj   +1 more source

Complement activation and increased anaphylatoxin receptor expression are associated with cortical grey matter lesions and the compartmentalised inflammatory response of multiple sclerosis

Frontiers in Cellular Neuroscience, 2023
BackgroundThe extent of cortical pathology is an important determinant of multiple sclerosis (MS) severity. Cortical demyelination and neurodegeneration are related to inflammation of the overlying leptomeninges, a more inflammatory CSF milieu and with ...
Rhian Evans, Lewis M. Watkins, Kristen Hawkins, Gabriella Santiago, Constantinos Demetriou, Michelle Naughton, Marie Dittmer, Mark I. Rees, Denise Fitzgerald, B. Paul Morgan, James W. Neal, Owain W. Howell   +11 more
doaj   +1 more source

Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer

Journal for ImmunoTherapy of Cancer, 2021
Background Resistance to therapy is a major problem in treating head and neck squamous cell carcinomas (HNSCC). Complement system inhibition has been shown to reduce tumor growth, metastasis, and therapeutic resistance in other tumor models, but has yet ...
Emily K Kleczko, Raphael A Nemenoff, Michael William Knitz   +2 more
doaj   +1 more source

Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b

Journal of Immunology, 2020
Key Points Complement receptor 3 forms a high-affinity complex with iC3b. In solution, iC3b appears to have a preferred location of the thioester domain. The CR3 headpiece molecule is valuable for analysis of receptor–ligand interactions.
R. K. Jensen, G. Bajic, M. Sen, T. Springer, T. Vorup-Jensen, G. Andersen   +5 more
semanticscholar   +1 more source

Role of Mac-1 integrin in generation of extracellular vesicles with antibacterial capacity from neutrophilic granulocytes

Journal of Extracellular Vesicles, 2020
Production of extracellular vesicles (EVs) involved in intercellular communication is a common capacity of most cell types. Upon encountering opsonized microorganisms, neutrophilic granulocytes release EVs that compromise bacterial growth. We carried out
Ákos M. Lőrincz, Balázs Bartos, Dávid Szombath, Viktória Szeifert, Csaba I. Timár, Lilla Turiák, László Drahos, Ágnes Kittel, Dániel S. Veres, Ferenc Kolonics, Attila Mócsai, Erzsébet Ligeti   +11 more
doaj   +1 more source