Results 351 to 360 of about 24,757,633 (403)
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The Complement System in Uremia
Scandinavian Journal of Urology and Nephrology, 1980Plasma C1q, C1 esterase inactivator, C4, C3 and C3 proactivator were measured in 20 chronic uremic patients on maintenance hemodialysis, in 10 conservatively treated chronic uremic patients and in 20 healthy volunteers. There was no statistical significant difference between the patient groups in any of the measured complement components.
Erik Stoffersen, K. Anker Jørgensen
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Pathways to the Complement System
New England Journal of Medicine, 1972IT has been well appreciated for many years that the serum complement system, through the concerted action of all its components, is a prime mediator of cytotoxic injury to antibody-sensitized cell...
Fred S. Rosen, Irwin H. Lepow
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Proteases of the complement system
Biochemical Society Transactions, 2004The complement system is a group of about 35 soluble and cell-surface proteins which interact to recognize, opsonize and clear or kill invading micro-organisms or altered host cells (e.g. apoptotic or necrotic cells). Complement is a major part of the innate immune system.
Stefanos A. Tsiftsoglou, Robert B. Sim
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Targeting the complement system
Current Opinion in Nephrology and Hypertension, 1999Interest has blossomed in the development of complement inhibitors, in parallel with a growth in our understanding of the biology of the complement cascade. The first generation of designed inhibitors was based on naturally occurring complement receptors and regulatory molecules.
James Marsh +2 more
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2002
The complement system is a vital part of the immune system in humans. It is composed of a group of highly coupled proteins that interact with one another to effect inflammation and the humoral immunity fly. Important aspects of the function of the complement system in triggering action in humans include the following [2]: 1.
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The complement system is a vital part of the immune system in humans. It is composed of a group of highly coupled proteins that interact with one another to effect inflammation and the humoral immunity fly. Important aspects of the function of the complement system in triggering action in humans include the following [2]: 1.
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Serpins and the Complement System
2011C1-inhibitor (serpin G1) is a 105 kDa inhibitor which functions as a major antiinflammatory protein in the body. It has its effects via inhibition of the proteases of the complement system and contact system of coagulation, as well as several direct effects mediated by its unique highly glycosylated N-terminal domain.
Péter Závodszky +6 more
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1979
The focus of discussion in this chapter will be the distribution of those items that we have analyzed as being complementizers. It will be particularly concerned with the phenomenon known traditionally as the ‘Double Relative’ construction (see the references in note 8 of Chapter 2).
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The focus of discussion in this chapter will be the distribution of those items that we have analyzed as being complementizers. It will be particularly concerned with the phenomenon known traditionally as the ‘Double Relative’ construction (see the references in note 8 of Chapter 2).
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The complement system in xenotransplantation
Immunopharmacology, 1992The immediate barrier to xenotransplantation across phylogenetically distant species, a manifestation of natural immunity, is hyperacute rejection of the xenograft. Complement (C) plays a central pathophysiological role in hyperacute rejection. Hyperacute rejection is initiated when C is activated by natural antibodies against the vascular endothelium ...
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Introduction to the complement system
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1984Complement is the essential effector mechanism in humoral immunity to infection. Combination of antibody with antigen causes cross-linking, leading to precipitation of soluble antigens and agglutination of particular antigens, but no more.
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The Complement System and Inflammation
1979The complement system was discovered toward the end of the nineteenth century as a heat-labile principle in fresh nonimmune serum which was essential for the bactericidal activity of serum from immunized guinea pigs. It has subsequently been established as a very important factor of constitutive immunity. The complement system functions as an auxiliary
Joe O. Minta, Henry Z. Movat
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