Results 231 to 240 of about 801,714 (279)

Molecular cloning and characterization of rabbit sex hormone binding globulin (SHBG) complementary DNA

, 1995
Alex Tu Wai-ki
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Understanding the Fidelity and Specificity of DNA Polymerase I. [PDF]

ACS Omega
Miller BR, Yeager AV, Collins JA, Beane A, Blake A, Tate E, Parish CA, Wu EY.   +7 more
europepmc   +1 more source

Evaluation of Plasma Donor-Derived Cell-Free DNA and the LASHA Scoring System as Complementary Tools in Lung Transplantation: Insights from a Prospective Single-Center Experience [PDF]

Federica Pezzuto, V. Tauro, Cecilia De Chellis, Francesca Lunardi, M. Loy, Eleonora Faccioli, Marta Vadori, Davide Biondini, S. Marinello, Fausto Braccioni, Marco Schiavon, Deborah Levine, Emanuele Cozzi, Federico Rea, F. Calabrese   +14 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

NapR, a novel nucleoid-associated protein, regulates antioxidant defense in mycobacteria. [PDF]

mSphere
Wang K, Cui X, Zhang X, Zheng J, Ling X, Zhang Y, Yu P, Lv B, Li W.   +8 more
europepmc   +1 more source

Transcription of complementary strands of phage lambda-DNA in vivo and in vitro.

, 1967
Stanley N. Cohen, J Hurwitz
openalex   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

RAD51 D-loop structures reveal the mechanism of eukaryotic RAD51-mediated strand exchange. [PDF]

Nat Commun
Luo SC, Yang CH, Yeh HY, Lin CW, Yeh MC, Chi P, Ho MC.   +6 more
europepmc   +1 more source