Results 211 to 220 of about 806,056 (297)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Engineering polymeric RNA scaffolds as programmable combinatorial innate immune agonists. [PDF]

Nucleic Acids Res
Yang Y, Alvarez AK, Wang W, Issa ECD, Dorsey E, Wu C.   +5 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Integrative Forensic Genetics, Biochemical, and Histological Methods for Reconstructing Biological Profiles from Aged Human Skeletal Remains. [PDF]

Genes (Basel)
Zupanič Pajnič I, Leskovar T.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Distance-Dependent Energy Transfer Between Organic Fluorophores and Single-Walled Carbon Nanotubes. [PDF]

Angew Chem Int Ed Engl
Kamińska I, Metternich JT, Szalai AM, Smidoda C, Chakraborty S, Vukovic L, Kruss S, Tinnefeld P.   +7 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Fully Automated Complementary DNA Microarray Segmentation using a Novel Fuzzy-based Algorithm.

J Med Signals Sens, 2015
Saberkari H, Bahrami S, Shamsi M, Amoshahy MJ, Ghavifekr HB, Sedaaghi MH.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Turning on Protein Function Inhibited by DNA Aptamers Employing a Covalent DNA-Binding Protein. [PDF]

ACS Nanosci Au
Kanazu T, Komiya E, Miura D, Tsukakoshi K, Ikebukuro K, Yamazaki T, Asano R.   +6 more
europepmc   +1 more source