Results 31 to 40 of about 3,270,422 (387)

Titanium Dioxide Nanoparticle-Based Interdigitated Electrodes: A Novel Current to Voltage DNA Biosensor Recognizes E. coli O157:H7. [PDF]

open access: yesPLoS ONE, 2015
Nanoparticle-mediated bio-sensing promoted the development of novel sensors in the front of medical diagnosis. In the present study, we have generated and examined the potential of titanium dioxide (TiO2) crystalline nanoparticles with aluminium ...
Sh Nadzirah   +4 more
doaj   +1 more source

Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly [PDF]

open access: yesPhysica A, 350 (2005) 89-94, 2005
DNA melting and hybridization is a fundamental biological process as well as a crucial step in many modern biotechnology applications. DNA confined on surfaces exhibits different behavior from that in free solutions. The system of DNA-capped gold nanoparticles exhibits unique phase transitions and represents a new class of complex fluids.
arxiv   +1 more source

Complementary DNA for human T-cell cyclophilin. [PDF]

open access: yesThe EMBO Journal, 1987
Complementary DNA encoding human cyclophilin, a specific cyclosporin A-binding protein, has been isolated from the leukemic T-cell line Jurkat and sequenced. Comparison of the deduced amino acid sequence with the previously determined sequence of bovine thymus cyclophilin reveals only three differences: an additional amino acid at the carboxy terminus ...
B Haendler   +2 more
openaire   +2 more sources

Comprehensive view of microscopic interactions between DNA-coated colloids [PDF]

open access: yes, 2021
The self-assembly of DNA-coated colloids into highly-ordered structures offers great promise for advanced optical materials. However, control of disorder, defects, melting, and crystal growth is hindered by the lack of a microscopic understanding of DNA-mediated colloidal interactions. Here we use total internal reflection microscopy to measure in situ
arxiv   +1 more source

The Enhanced Sensitivity of a Porous Silicon Microcavity Biosensor Based on an Angular Spectrum Using CdSe/ZnS Quantum Dots

open access: yesSensors, 2019
To improve the detection sensitivity of porous silicon microcavity biosensors, CdSe/ZnS quantum dots are used to label complementary DNA molecules for the refractive index amplification and angular spectrum method for detection.
Rui Zhou   +3 more
doaj   +1 more source

Why are complementary DNA strands symmetric? [PDF]

open access: yesBioinformatics, 2002
Abstract Motivation: Over sufficiently long windows, complementary strands of DNA tend to have the same base composition. A few reports have indicated that this first-order parity rule extends at higher orders to oligonucleotide composition, at least in some organisms or taxa. However, the scientific literature falls short of providing a
Pierre Baldi   +2 more
openaire   +3 more sources

Molecular Spiders in One Dimension [PDF]

open access: yes, 2007
Molecular spiders are synthetic bio-molecular systems which have "legs" made of short single-stranded segments of DNA. Spiders move on a surface covered with single-stranded DNA segments complementary to legs.
Alberts B   +21 more
core   +4 more sources

Insights into DNA-mediated interparticle interactions from a coarse-grained model [PDF]

open access: yesJ. Chem. Phys. 141, 184901 (2014), 2015
DNA-functionalized particles have great potential for the design of complex self-assembled materials. The major hurdle in realizing crystal structures from DNA-functionalized particles is expected to be kinetic barriers that trap the system in metastable amorphous states.
arxiv   +1 more source

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined “Complementary Lethality”

open access: yesMolecular Therapy: Nucleic Acids, 2013
A high mutation rate leading to tumor cell heterogeneity is a driver of malignancy in human cancers. Paradoxically, however, genomic instability can also render tumors vulnerable to therapeutic attack. Thus, targeting DNA repair may induce an intolerable
Mateusz Rytelewski   +5 more
doaj   +1 more source

Structural assessment of the full-length wild-type tumor suppressor protein p53 by mass spectrometry-guided computational modeling

open access: yesScientific Reports, 2023
The tetrameric tumor suppressor p53 represents a great challenge for 3D-structural analysis due to its high degree of intrinsic disorder (ca. 40%). We aim to shed light on the structural and functional roles of p53’s C-terminal region in full-length ...
Alessio Di Ianni   +8 more
doaj   +1 more source

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