Results 31 to 40 of about 3,266,061 (366)
Communications Biology, 2022 The DNA origami design algorithm DAEDALUS is modified to design a nanoscale cube with a two-step assembly protocol, assembling 9 modules from three DNA scaffolds and the complementary staples, combined to form the DNA origami cube.
Linfeng Cao +8 more
doaj +1 more source
Base Orientation of Second DNA in RecA·DNA Filaments. Analysis by combination of linear dichroism and small angle neutron scattering in flow-oriented solution [PDF]
, 1998 To gain insight into the mechanism of pairing two complementary DNA strands by the RecA protein, we have determined the nucleobase orientation of the first and the second bound DNA strands in the RecA·DNA filament by combined measurements of linear ...
Ellouze, Christine +5 more
core +1 more source
A highly sensitive electrochemical genosensor based on Co-porphyrin-labelled DNA [PDF]
, 2014 We report the use of Co-porphyrins as electrochemical tags for a highly sensitive and selective genosensor. An avian influenza virus-based DNA sequence characteristic of H5N1 was detected at femtomolar levels from competing non-complementary sequences ...
Grabowska, Iwona +8 more
core +1 more source
Titanium Dioxide Nanoparticle-Based Interdigitated Electrodes: A Novel Current to Voltage DNA Biosensor Recognizes E. coli O157:H7. [PDF]
PLoS ONE, 2015 Nanoparticle-mediated bio-sensing promoted the development of novel sensors in the front of medical diagnosis. In the present study, we have generated and examined the potential of titanium dioxide (TiO2) crystalline nanoparticles with aluminium ...
Sh Nadzirah +4 more
doaj +1 more source
Why are complementary DNA strands symmetric? [PDF]
Bioinformatics, 2002 Abstract Motivation: Over sufficiently long windows, complementary strands of DNA tend to have the same base composition. A few reports have indicated that this first-order parity rule extends at higher orders to oligonucleotide composition, at least in some organisms or taxa. However, the scientific literature falls short of providing a
Pierre Baldi +2 more
openaire +3 more sources
Sensors, 2019 To improve the detection sensitivity of porous silicon microcavity biosensors, CdSe/ZnS quantum dots are used to label complementary DNA molecules for the refractive index amplification and angular spectrum method for detection.
Rui Zhou +3 more
doaj +1 more source
Complementary DNA for human T-cell cyclophilin. [PDF]
The EMBO Journal, 1987 Complementary DNA encoding human cyclophilin, a specific cyclosporin A-binding protein, has been isolated from the leukemic T-cell line Jurkat and sequenced. Comparison of the deduced amino acid sequence with the previously determined sequence of bovine thymus cyclophilin reveals only three differences: an additional amino acid at the carboxy terminus ...
B Haendler +2 more
openaire +2 more sources
Molecular Spiders in One Dimension [PDF]
, 2007 Molecular spiders are synthetic bio-molecular systems which have "legs" made of short single-stranded segments of DNA. Spiders move on a surface covered with single-stranded DNA segments complementary to legs.
Alberts B +21 more
core +4 more sources
Molecular Therapy: Nucleic Acids, 2013 A high mutation rate leading to tumor cell heterogeneity is a driver of malignancy in human cancers. Paradoxically, however, genomic instability can also render tumors vulnerable to therapeutic attack. Thus, targeting DNA repair may induce an intolerable
Mateusz Rytelewski +5 more
doaj +1 more source
Scientific Reports, 2023 The tetrameric tumor suppressor p53 represents a great challenge for 3D-structural analysis due to its high degree of intrinsic disorder (ca. 40%). We aim to shed light on the structural and functional roles of p53’s C-terminal region in full-length ...
Alessio Di Ianni +8 more
doaj +1 more source