Results 71 to 80 of about 3,266,061 (366)
Cloning of complementary DNA encoding a functional human interleukin-8 receptor.
Science, 1991 Interleukin-8 (IL-8) is an inflammatory cytokine that activates neutrophil chemotaxis, degranulation, and the respiratory burst. Neutrophils express receptors for IL-8 that are coupled to guanine nucleotide-binding proteins (G proteins); binding of IL-8 ...
P. Murphy, H. Tiffany
semanticscholar +1 more source
Colloidal Flying Carpets [PDF]
, 2009 DNA plays a special role in polymer science not just because of the highly selective recognition of complementary single DNA strands but also because bacteria can express DNA chains that are very long yet perfectly monodisperse.
Eiser, Erika, Geerts, Nienke
core +1 more source
Bubble propagation in a helicoidal molecular chain
, 2000 We study the propagation of very large amplitude localized excitations in a model of DNA that takes explicitly into account the helicoidal structure. These excitations represent the ``transcription bubble'', where the hydrogen bonds between complementary
A. Campa +30 more
core +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Non-homologous DNA end joining in normal and cancer cells and its dependence on break structures
Genetics and Molecular Biology, 2010 DNA double-strand breaks (DSBs) are a serious threat to the cell, for if not or miss-repaired, they can lead to chromosomal aberration, mutation and cancer.
Tomasz Poplawski +2 more
doaj
Experimental validation of determinants of UV sensitivity using synthetic DNA
Journal of Photochemistry and Photobiology, 2022 Treatment with ultraviolet (UV) light has been shown to be effective for disinfection of pathogens. For pathogenic risk management, it would be effective to estimate the UV sensitivity of unknown pathogenic microorganisms from their nucleotide sequences.
M. Otaki, Y. Higashino, Y. Yamada
doaj
Simulations Meet Experiment to Reveal New Insights into DNA Intrinsic Mechanics.
PLoS Computational Biology, 2015 The accurate prediction of the structure and dynamics of DNA remains a major challenge in computational biology due to the dearth of precise experimental information on DNA free in solution and limitations in the DNA force-fields underpinning the ...
Akli Ben Imeddourene +5 more
doaj +1 more source
The process of infection with bacteriophage phiX174, XXX. Replication of double-stranded phiX DNA [PDF]
, 1969 Intermediates involved in the replication of double-stranded phiX174 RF DNA have been identified and partially characterized. Analysis of pulse-labeled RF DNA suggests that the synthesis of progeny RF molecules involves, in part, the addition of ...
Knippers, Rolf +2 more
core
Sensitive detection of multiple pathogens using a single DNA probe [PDF]
, 2016 A simple but promising electrochemical DNA nanosensor was designed, constructed and applied to differentiate a few food-borne pathogens. The DNA probe was initially designed to have a complementary region in Vibrio parahaemolyticus (VP) genome and to ...
Abdullah, Jaafar +4 more
core +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source