Results 121 to 130 of about 208,635 (246)

A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4 [PDF]

, 2013
Andrew Perry, Lakshmi C. Wijeyewickrema, Pascal G. Wilmann, Menachem J. Gunzburg, Laura D’Andrea, James A. Irving, Siew Siew Pang, Renee C. Duncan, Matthew C. J. Wilce, James C. Whisstock, Robert N. Pike   +10 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Stability of complement value problems for $p$-Lévy operators [PDF]

, 2023
Guy Foghem
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Paroxysmal cold hemoglobinuria successfully treated with complement inhibition [PDF]

, 2019
Sarah A. Lau-Braunhut, Hannah Stone, Griffin Collins, Sigbjørn Berentsen, Benjamin S. Braun, Matt S. Zinter   +5 more
openalex   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Restricted Complement Activation by Escherichia Coli with the K-1 Capsular Serotype: A Possible Role in Pathogenicity [PDF]

, 1978
Paul Stevens, Shena N-Y. Huang, William D. Welch, Lowell S. Young   +3 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Generation of exogenous kidneys via CRISPR/Cas9 mediated blastocyst complementation targeting Osr1 gene in mice. [PDF]

Sci Rep
Yeh TY, Chiu IM, Huang YJ, Wu SC, Hsieh CC, Sung HH, Hwu WL, Wang GJ, Ju JC.   +8 more
europepmc   +1 more source