Results 81 to 90 of about 220,316 (319)
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Every Hilbert space frame has a Naimark complement [PDF]
Naimark complements for Hilbert space Parseval frames are one of the most fundamental and useful results in the field of frame theory. We will show that actually all Hilbert space frames have Naimark complements which possess all the usual properties for Naimark complements with one notable exception.
arxiv
Acquisition of complementation
ABSTRACTThis study concerns the acquisition of complex sentences with perception and epistemic verbs that take a second verb in their complements. The acquisition of complementation began between two and three years of age in this longitudinal study of four children's spontaneous speech.
Bloom, Lois+3 more
openaire +5 more sources
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Leinert sets and complemented ideals in Fourier algebras [PDF]
Let $G$ be a locally compact group. We show how complemented ideals in the Fourier algebra $A(G)$ of $G$ arise naturally from a class of thin sets known as Leinert sets. Moreover, we also present an explicit example of a closed ideal in $A(\mathbb{F}_{N})$, the free group on $N \ge 2$ generators, that is complemented in $A(\mathbb{F}_{N})$ but it is ...
arxiv
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
NPS6 is one of the nonribosomal peptide synthetase (NRPS) family members. The roles of NPS6 in ascomycetes are well known, but its roles in Fusarium oxysporum are unidentified.
Jiaqi Li+6 more
doaj +1 more source
When is the sum of complemented subspaces complemented? [PDF]
We provide a sufficient condition for the sum of a finite number of complemented subspaces of a Banach space to be complemented. Under this condition a formula for a projection onto the sum is given. We also show that the condition is sharp (in a certain sense).
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source