Results 81 to 90 of about 995,191 (403)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Phenotypes Associated with Second Chromosome P Element Insertions in Drosophila melanogaster

open access: yesG3: Genes, Genomes, Genetics, 2016
In Drosophila melanogaster, P element transposition has been a productive means of insertional mutagenesis. Thousands of genes have been tagged with natural and engineered P element constructs. Nevertheless, chromosomes carrying P element insertions tend
Lily Kahsai   +2 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

A gene-specific T2A-GAL4 library for Drosophila

open access: yeseLife, 2018
We generated a library of ~1000 Drosophila stocks in which we inserted a construct in the intron of genes allowing expression of GAL4 under control of endogenous promoters while arresting transcription with a polyadenylation signal 3’ of the GAL4.
Pei-Tseng Lee   +21 more
doaj   +1 more source

Complementation contributes to transcriptome complexity in maize (Zea mays L.) hybrids relative to their inbred parents

open access: yesGenome Research, 2012
Typically, F1-hybrids are more vigorous than their homozygous, genetically distinct parents, a phenomenon known as heterosis. In the present study, the transcriptomes of the reciprocal maize (Zea mays L.) hybrids B73×Mo17 and Mo17×B73 and their parental ...
Anja Paschold   +10 more
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Decidability of Existence and Construction of a Complement of a given Function [PDF]

open access: yesarXiv, 2011
This article defines a complement of a function and conditions for existence of such a complement function and presents few algorithms to construct a complement.
arxiv  

How unprovable is Rabin's decidability theorem?

open access: yes, 2015
We study the strength of set-theoretic axioms needed to prove Rabin's theorem on the decidability of the MSO theory of the infinite binary tree. We first show that the complementation theorem for tree automata, which forms the technical core of typical ...
Beckmann A.   +6 more
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

USO DE BLOQUES NUTRICIONALES COMO COMPLEMENTO PARA OVINOS EN EL TROPICO SECO DEL ALTIPLANO CENTRAL DE MEXICO

open access: yesTropical and Subtropical Agroecosystems, 2012
El objetivo del estudio fue evaluar el comportamiento productivo de ovinos complementados con bloques nutricionales en confinamiento y pastoreo. Se llevaron a cabo dos experimentos, el Experimento 1 se realizó con ovinos en confinamiento, el Experimento
Paulina Vazquez-Mendoza   +4 more
doaj  

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